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Ace3 Gene Detail
Summary
  • Symbol
    Ace3
  • Name
    angiotensin I converting enzyme (peptidyl-dipeptidase A) 3
  • Synonyms
    EG217246
  • Feature Type
    protein coding gene
  • IDs
    MGI:3644400
    NCBI Gene: 217246
Location & Maps
more
  • Sequence Map
    Chr11:105994675-106005443 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10769 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 68.86 cM
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    ACE3P, angiotensin I converting enzyme (peptidyl-dipeptidase A) 3, pseudogene
  • Vertebrate Orthologs
    4
  • Human Ortholog
    ACE3P, angiotensin I converting enzyme (peptidyl-dipeptidase A) 3, pseudogene
    Orthology source: HGNC
  • Synonyms
    ACE3
  • Links
    NCBI Gene ID: 100129123

  • Chr Location
    17q23.3; chr17:63507034-63519827 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype reference
  • All Mutations and Alleles
    1
  • Targeted
    1
Male mice homozygous for a knock-out allele exhibit normal sperm number, motility, and fertilization ability.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033693 VEGA Gene Model | MGI Sequence Detail 10769 C57BL/6J ±  kb
transcript OTTMUST00000084872 VEGA | MGI Sequence Detail 2214 Not Applicable  
polypeptide OTTMUSP00000062952 VEGA | MGI Sequence Detail 737 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    44 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR001548 Peptidase M2, peptidyl-dipeptidase A
Molecular
Reagents
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  • All nucleic 2
    cDNA 2
References
more
  • Summaries
    All 13
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 1
  • Earliest
    J:123156 Rella M, et al., Identification and characterisation of the angiotensin converting enzyme-3 (ACE3) gene: a novel mammalian homologue of ACE. BMC Genomics. 2007;8:194
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory