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C1s2 Gene Detail
Summary
  • Symbol
    C1s2
  • Name
    complement component 1, s subcomponent 2
  • Synonyms
    Gm5077
  • Feature Type
    protein coding gene
  • IDs
    MGI:3644269
    NCBI Gene: 317677
  • Gene Overview
    MyGene.info: C1S
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr6:124624625-124636085 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 59.17 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    204 from dbSNP Build 142
  • Strain Annotations
    10
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3644269
protein coding gene Chr6:124624625-124641894 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0031227
protein coding gene Chr6:123099758-123127152 (-)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0031235
protein coding gene Chr6:122669935-122702748 (-)
C3H/HeJ MGP_C3HHeJ_G0030958
protein coding gene Chr6:126378598-126400031 (-)
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0030919
protein coding gene Chr6:136322005-136336117 (-)
DBA/2J MGP_DBA2J_G0031075
protein coding gene Chr6:122028218-122043654 (-)
FVB/NJ MGP_FVBNJ_G0031025
protein coding gene Chr6:120942484-120954201 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0031063
protein coding gene Chr6:140255342-140278302 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031726
protein coding gene Chr6:126355786-126369297 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0030424
protein coding gene Chr6:126694537-126728857 (-)



Homology
more
  • Human Ortholog
    C1S, complement C1s
  • Vertebrate Orthologs
    10
  • Human Ortholog
    C1S, complement C1s
    Orthology source: HGNC, HomoloGene
  • Synonyms
    EDSPD2
  • Links
    NCBI Gene ID: 716
    neXtProt AC: NX_P09871
    UniProt: P09871

  • Chr Location
    12p13.31; chr12:7060676-7071032 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000079343 Ensembl Gene Model | MGI Sequence Detail 11461 C57BL/6J ±  kb
transcript ENSMUST00000218020 Ensembl | MGI Sequence Detail 2662 Not Applicable  
polypeptide ENSMUSP00000151642 Ensembl | MGI Sequence Detail 694 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 20
    Gene Ontology 6
    Phenotypes 3
  • Earliest
    J:83033 Garnier G, et al., Complement C1r and C1s genes are duplicated in the mouse: differential expression generates alternative isomorphs in the liver and in the male reproductive system. Biochem J. 2003 Apr 15;371(Pt 2):631-40
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory