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Ttll2 Gene Detail
Summary
  • Symbol
    Ttll2
  • Name
    tubulin tyrosine ligase-like family, member 2
  • Synonyms
    EG625850
  • Feature Type
    protein coding gene
  • IDs
    MGI:3644030
    NCBI Gene: 100216474
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr17:7350885-7352696 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 4.72 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    17 from dbSNP Build 142
  • Strain Annotations
    12
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3644030
protein coding gene Chr17:7350626-7364035 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023119
protein coding gene Chr17:4623258-4624980 (-)
A/J no annotation
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0023094
protein coding gene Chr17:4669136-4670928 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0023534
protein coding gene Chr17:4886921-4888713 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021075
protein coding gene Chr17:9089010-9090799 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0022822
protein coding gene Chr17:5095330-5097122 (-)
DBA/2J MGP_DBA2J_G0022994
protein coding gene Chr17:10262053-10263845 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0023026
protein coding gene Chr17:4877126-4881456 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0023599
protein coding gene Chr17:10741896-10743689 (-)
PWK/PhJ MGP_PWKPhJ_G0022113
protein coding gene Chr17:4114083-4115876 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021943
protein coding gene Chr17:4455329-4457121 (+)
WSB/EiJ MGP_WSBEiJ_G0022421
protein coding gene Chr17:4825274-4826721 (-)



Homology
more
  • Human Ortholog
    TTLL2, tubulin tyrosine ligase like 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TTLL2, tubulin tyrosine ligase like 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C6orf104, dJ366N23.3, NYD-TSPG
  • Links
    NCBI Gene ID: 83887
    neXtProt AC: NX_Q9BWV7
    UniProt: Q9BWV7

  • Chr Location
    6q27; chr6:167325086-167342710 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 12917
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TTLL2
  • Gene Tree
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000079722 Ensembl Gene Model | MGI Sequence Detail 1812 C57BL/6J ±  kb
transcript ENSMUST00000115747 Ensembl | MGI Sequence Detail 1642 Not Applicable  
polypeptide ENSMUSP00000111413 Ensembl | MGI Sequence Detail 540 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1
Other
Accession IDs
less
MGI:3779421
References
more
  • Summaries
    All 14
    Gene Ontology 2
  • Earliest
    J:130247 van Dijk J, et al., A targeted multienzyme mechanism for selective microtubule polyglutamylation. Mol Cell. 2007 May 11;26(3):437-48
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/18/2019
MGI 6.14
The Jackson Laboratory