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Mylk4 Gene Detail
Summary
  • Symbol
    Mylk4
  • Name
    myosin light chain kinase family, member 4
  • Synonyms
    EG238564
  • Feature Type
    protein coding gene
  • IDs
    MGI:3643758
    NCBI Gene: 238564
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:32700827-32783954 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 13.72 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    439 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3643758
 protein coding gene Chr13:32700824-32806773 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020425
 protein coding gene Chr13:30698822-30786296 (-)
A/J MGP_AJ_G0020380
 protein coding gene Chr13:29863056-29947488 (-)
AKR/J MGP_AKRJ_G0020357
 protein coding gene Chr13:30516289-30607793 (-)
BALB/cJ MGP_BALBcJ_G0020375
 protein coding gene Chr13:29948486-30032022 (-)
C3H/HeJ MGP_C3HHeJ_G0020178
 protein coding gene Chr13:30505210-30592752 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020811
 protein coding gene Chr13:31728544-31821802 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018402
 protein coding gene Chr13:28187149-28268898 (-)
CAST/EiJ MGP_CASTEiJ_G0019695
 protein coding gene Chr13:30219729-30325000 (-)
CBA/J MGP_CBAJ_G0020134
 protein coding gene Chr13:33097455-33185461 (-)
DBA/2J MGP_DBA2J_G0020256
 protein coding gene Chr13:29365632-29451676 (-)
FVB/NJ MGP_FVBNJ_G0020241
 protein coding gene Chr13:28973298-29059997 (-)
LP/J MGP_LPJ_G0020333
 protein coding gene Chr13:30904074-30987697 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020267
 protein coding gene Chr13:33156116-33249764 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020852
 protein coding gene Chr13:30163356-30250236 (-)
PWK/PhJ MGP_PWKPhJ_G0019450
 protein coding gene Chr13:29548167-29637043 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019271
 protein coding gene Chr13:29091589-29179797 (-)
WSB/EiJ MGP_WSBEiJ_G0019757
 protein coding gene Chr13:30485763-30572318 (-)



Homology
more
  • Human Ortholog
    MYLK4, myosin light chain kinase family member 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MYLK4, myosin light chain kinase family member 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SgK085
  • Links
    NCBI Gene ID: 340156
    neXtProt AC: NX_Q86YV6
    UniProt: Q86YV6

  • Chr Location
    6p25.2; chr6:2663629-2770330 (-)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    631
  • cDNA Data
    4
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000044951 Ensembl Gene Model | MGI Sequence Detail 83128 C57BL/6J ±  kb
transcript ENSMUST00000238977 Ensembl | MGI Sequence Detail 6570 Not Applicable  
polypeptide ENSMUSP00000159085 Ensembl | MGI Sequence Detail 667 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 1
References
more
  • Summaries
    All 24
    Gene Ontology 1
    Phenotypes 10
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:234274 Chang AN, et al., Cardiac myosin light chain is phosphorylated by Ca2+/calmodulin-dependent and -independent kinase activities. Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):E3824-33
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/13/2020
MGI 6.16 		The Jackson Laboratory