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Mylk4 Gene Detail
Summary
  • Symbol
    Mylk4
  • Name
    myosin light chain kinase family, member 4
  • Synonyms
    EG238564
  • Feature Type
    protein coding gene
  • IDs
    MGI:3643758
    NCBI Gene: 238564
  • Alliance
    gene page
Location & Maps
more
  • Sequence Map
    Chr13:32704680-32783954 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      79275 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 13.72 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    MYLK4, myosin light chain kinase family member 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MYLK4, myosin light chain kinase family member 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SgK085
  • Links
    NCBI Gene ID: 340156
    neXtProt AC: NX_Q86YV6
    UniProt: Q86YV6

  • Chr Location
    6p25.2; chr6:2663629-2770330 (-)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    3
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000690 VEGA Gene Model | MGI Sequence Detail 79275 C57BL/6J ±  kb
transcript OTTMUST00000001322 VEGA | MGI Sequence Detail 1722 Not Applicable  
polypeptide OTTMUSP00000000621 VEGA | MGI Sequence Detail 386 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    428 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000029127 myosin light chain kinase family member 4
    (term hierarchy)
  • InterPro Domains
    IPR020636 Calcium/calmodulin-dependent/calcium-dependent protein kinase
    IPR017441 Protein kinase, ATP binding site
    IPR000719 Protein kinase domain
    IPR011009 Protein kinase-like domain superfamily
    IPR008271 Serine/threonine-protein kinase, active site
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 1
References
more
  • Summaries
    All 23
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:141688 Goldsworthy M, et al., Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance. Diabetes. 2008 Aug;57(8):2234-44
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/10/2017
MGI 6.10 		The Jackson Laboratory