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Sfta2 Gene Detail
Summary
  • Symbol
    Sfta2
  • Name
    surfactant associated 2
  • Synonyms
    EG433102
  • Feature Type
    protein coding gene
  • IDs
    MGI:3643293
    NCBI Gene: 433102
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:35649708-35650569 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 18.70 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3643293
protein coding gene Chr17:35601549-35650571 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023646
protein coding gene Chr17:35780910-35834328 (+)
A/J MGP_AJ_G0023601
protein coding gene Chr17:34676137-34729060 (+)
AKR/J MGP_AKRJ_G0023571
protein coding gene Chr17:35088667-35155445 (+)
BALB/cJ MGP_BALBcJ_G0023606
protein coding gene Chr17:34812390-34861304 (+)
C3H/HeJ MGP_C3HHeJ_G0023372
protein coding gene Chr17:35550058-35615624 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024048
protein coding gene Chr17:37245467-37300549 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021526
protein coding gene Chr17:32380604-32427098 (+)
CAST/EiJ MGP_CASTEiJ_G0022863
protein coding gene Chr17:35664717-35716569 (+)
CBA/J MGP_CBAJ_G0023350
protein coding gene Chr17:38801703-38869550 (+)
DBA/2J MGP_DBA2J_G0023474
protein coding gene Chr17:33990463-34041233 (+)
FVB/NJ MGP_FVBNJ_G0023445
protein coding gene Chr17:33783357-33833352 (+)
LP/J MGP_LPJ_G0023554
protein coding gene Chr17:36162958-36216216 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023466
protein coding gene Chr17:37598585-37648817 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024091
protein coding gene Chr17:35415312-35469770 (+)
PWK/PhJ MGP_PWKPhJ_G0022614
protein coding gene Chr17:32843914-32893758 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022433
protein coding gene Chr17:33459458-33503620 (+)
WSB/EiJ MGP_WSBEiJ_G0022929
protein coding gene Chr17:35556384-35613396 (+)



Homology
more
  • Human Ortholog
    SFTA2, surfactant associated 2
  • Human Ortholog
    SFTA2, surfactant associated 2
    Orthology source: HGNC
  • Synonyms
    GSGL541, SFTPG, SP-G, UNQ541
  • Links
    NCBI Gene ID: 389376
    neXtProt AC: NX_Q6UW10
    UniProt: Q6UW10

  • Chr Location
    6p21.33; chr6:30931350-30932175 (-)  GRCh38.p7

  • HCOP
    human homology predictions: SFTA2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 433102 NCBI Gene Model | MGI Sequence Detail 862 C57BL/6J ±  kb
transcript NM_001163194 RefSeq | MGI Sequence Detail 506 C57BL/6  
polypeptide E9PXB6 UniProt | EBI | MGI Sequence Detail 77 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3
References
more
  • Summaries
    All 15
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:190754 Ermakova O, et al., Construction and phenotypic analysis of mice carrying a duplication of the major histocompatibility class I (MHC-I) locus. Mamm Genome. 2012 Aug;23(7-8):443-53

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/26/2019
MGI 6.14
The Jackson Laboratory