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Kctd21 Gene Detail
Summary
  • Symbol
    Kctd21
  • Name
    potassium channel tetramerisation domain containing 21
  • Synonyms
    EG622320
  • Feature Type
    protein coding gene
  • IDs
    MGI:3643121
    NCBI Gene: 622320
Location & Maps
more
  • Sequence Map
    Chr7:97332327-97350213 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      17887 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 53.47 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    KCTD21, potassium channel tetramerization domain containing 21
  • Vertebrate Orthologs
    8
  • Human Ortholog
    KCTD21, potassium channel tetramerization domain containing 21
    Orthology source: HomoloGene, HGNC
  • Synonyms
    KCASH2
  • Links
    NCBI Gene ID: 283219
    neXtProt AC: NX_Q4G0X4

  • Chr Location
    11q14.1; chr11:78171243-78188817 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    26 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    1
  • Gene trapped
    7
  • Radiation induced
    2
  • Targeted
    2
  • Genomic Mutations
    3 involving Kctd21
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029536 VEGA Gene Model | MGI Sequence Detail 17887 C57BL/6J ±  kb
transcript OTTMUST00000073209 VEGA | MGI Sequence Detail 2966 Not Applicable  
polypeptide OTTMUSP00000037870 VEGA | MGI Sequence Detail 260 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    177 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000032411 BTB/POZ domain-containing protein KCTD21
  • InterPro Domains
    IPR000210 BTB/POZ domain
    IPR003131 Potassium channel tetramerisation-type BTB domain
    IPR011333 SKP1/BTB/POZ domain
Molecular
Reagents
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  • All nucleic 10
    cDNA 10

    Microarray probesets 1
References
more
  • Summaries
    All 18
    Gene Ontology 1
    Phenotypes 26
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory