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Silc1 Gene Detail
Summary
  • Symbol
    Silc1
  • Name
    sciatic injury induced lincRNA upregulator of SOX11
  • Synonyms
    EG636791, Gm9866
  • Feature Type
    lncRNA gene
  • IDs
    MGI:3643118
    NCBI Gene: 636791
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:27190795-27210515 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 9.86 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    251 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3643118
 lncRNA gene Chr12:27100949-27210632 (-)
129S1/SvImJ MGP_129S1SvImJ_G0005349
 lincRNA gene Chr12:24904784-24924624 (-)
A/J MGP_AJ_G0005332
 lincRNA gene Chr12:24252614-24272556 (-)
AKR/J MGP_AKRJ_G0005312
 lincRNA gene Chr12:25023574-25044836 (-)
BALB/cJ MGP_BALBcJ_G0005314
 lincRNA gene Chr12:24502912-24522766 (-)
C3H/HeJ MGP_C3HHeJ_G0005263
 lincRNA gene Chr12:24932440-24953022 (-)
C57BL/6NJ MGP_C57BL6NJ_G0005468
 lincRNA gene Chr12:25719126-25739089 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0004855
 lincRNA gene Chr12:23665817-23685775 (-)
CAST/EiJ MGP_CASTEiJ_G0005210
 lincRNA gene Chr12:19910116-19930013 (-)
CBA/J MGP_CBAJ_G0005252
 lincRNA gene Chr12:26571364-26591189 (-)
DBA/2J MGP_DBA2J_G0005270
 lincRNA gene Chr12:24095820-24115600 (-)
FVB/NJ MGP_FVBNJ_G0005295
 lincRNA gene Chr12:23949433-23969168 (-)
LP/J MGP_LPJ_G0005351
 lincRNA gene Chr12:24991054-25010842 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0005277
 lincRNA gene Chr12:26269150-26289139 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0005470
 lincRNA gene Chr12:24591730-24611539 (-)
PWK/PhJ MGP_PWKPhJ_G0005159
 lincRNA gene Chr12:18834374-18854395 (-)
SPRET/EiJ MGP_SPRETEiJ_G0005079
 lincRNA gene Chr12:19091010-19111922 (-)
WSB/EiJ MGP_WSBEiJ_G0005258
 lincRNA gene Chr12:24795826-24815615 (-)



Homology
more
  • Human Ortholog
    SILC1, sciatic injury induced lincRNA upregulator of SOX11
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SILC1, sciatic injury induced lincRNA upregulator of SOX11
  • Synonyms
    LINC01105
  • Links
    NCBI Gene ID: 150622

  • Chr Location
    2p25.2; chr2:5932543-6003510 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele display impaired recovery from nerve crush injury.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
Sequences &
Gene Models
less
  • All Sequences
    45
  • RefSeq
    4
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 636791 NCBI Gene Model | MGI Sequence Detail 19721 C57BL/6J ±  kb
transcript NR_045868 RefSeq | MGI Sequence Detail 2087 C57BL/6  
polypeptide Q8C8T9 UniProt | EBI | MGI Sequence Detail 161 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 2
References
more
  • Summaries
    All 16
    Phenotypes 3
  • Earliest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
  • Latest
    J:341357 Ben-Tov Perry R, et al., Silc1 long noncoding RNA is an immediate-early gene promoting efficient memory formation. Cell Rep. 2023 Sep 22;42(10):113168
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory