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Neurl1b Gene Detail
Summary
  • Symbol
    Neurl1b
  • Name
    neuralized E3 ubiquitin protein ligase 1B
  • Synonyms
    C230078M08Rik, EG240055, Neur2
  • Feature Type
    protein coding gene
  • IDs
    MGI:3643092
    NCBI Gene: 240055
Location & Maps
more
  • Sequence Map
    Chr17:26414829-26446349 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      31521 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 13.18 cM
  • Mapping Data
    2 experiments
Homology
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  • Human Ortholog
    NEURL1B, neuralized E3 ubiquitin protein ligase 1B
  • Vertebrate Orthologs
    9
  • Human Ortholog
    NEURL1B, neuralized E3 ubiquitin protein ligase 1B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    hNeur2, neur2, NEURL3
  • Links
    NCBI Gene ID: 54492
    neXtProt AC: NX_A8MQ27

  • Chr Location
    5q35.1; chr5:172641247-172691540 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    4
  • Radiation induced
    2
  • Targeted
    2
  • Genomic Mutations
    2 involving Neurl1b
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000043222 VEGA Gene Model | MGI Sequence Detail 31521 C57BL/6J ±  kb
transcript OTTMUST00000113408 VEGA | MGI Sequence Detail 6195 Not Applicable  
polypeptide OTTMUSP00000063435 VEGA | MGI Sequence Detail 546 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    454 from dbSNP Build 142
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000031933 E3 ubiquitin-protein ligase NEURL1B
  • EC
  • InterPro Domains
    IPR006573 Neuralized homology repeat (NHR) domain
    IPR013083 Zinc finger, RING/FYVE/PHD-type
    IPR001841 Zinc finger, RING-type
Molecular
Reagents
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  • All nucleic 22
    Genomic 1
    cDNA 14
    Primer pair 4
    Other 3

    Microarray probesets 3
Other
Accession IDs
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MGI:2442659
References
more
  • Summaries
    All 24
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory