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Ddx43 Gene Detail
Summary
  • Symbol
    Ddx43
  • Name
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
  • Synonyms
    ENSMUSG00000070291, OTTMUSG00000019690
  • Feature Type
    protein coding gene
  • IDs
    MGI:3642857
    NCBI Gene: 100048658
  • Gene Overview
    MyGene.info: DDX43
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:78395777-78423587 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 43.65 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    80 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3642857
protein coding gene Chr9:78395777-78423589 (.)
129S1/SvImJ MGP_129S1SvImJ_G0035068
protein coding gene Chr9:78900435-78928560 (+)
A/J MGP_AJ_G0035049
protein coding gene Chr9:76176434-76204078 (+)
AKR/J MGP_AKRJ_G0034977
protein coding gene Chr9:77979384-78006958 (+)
BALB/cJ MGP_BALBcJ_G0035037
protein coding gene Chr9:75832845-75860545 (+)
C3H/HeJ MGP_C3HHeJ_G0034749
protein coding gene Chr9:78497147-78524887 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035558
protein coding gene Chr9:81021972-81050894 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032467
protein coding gene Chr9:75408222-75435667 (+)
CAST/EiJ MGP_CASTEiJ_G0034068
protein coding gene Chr9:78773601-78806075 (+)
CBA/J MGP_CBAJ_G0034722
protein coding gene Chr9:83884883-83912557 (+)
DBA/2J MGP_DBA2J_G0034880
protein coding gene Chr9:75817347-75845003 (+)
FVB/NJ MGP_FVBNJ_G0034823
protein coding gene Chr9:75047726-75075437 (+)
LP/J MGP_LPJ_G0034961
protein coding gene Chr9:79124776-79156256 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034865
protein coding gene Chr9:85064222-85103723 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035581
protein coding gene Chr9:78142808-78170472 (+)
PWK/PhJ MGP_PWKPhJ_G0033770
protein coding gene Chr9:76006936-76035823 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033607
protein coding gene Chr9:78341375-78374237 (+)
WSB/EiJ MGP_WSBEiJ_G0034183
protein coding gene Chr9:78091863-78119750 (+)



Homology
more
  • Human Ortholog
    DDX43, DEAD-box helicase 43
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DDX43, DEAD-box helicase 43
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CT13, HAGE
  • Links
    NCBI Gene ID: 55510
    neXtProt AC: NX_Q9NXZ2
    UniProt: Q9NXZ2

  • Chr Location
    6q13; chr6:73394562-73417566 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000070291 Ensembl Gene Model | MGI Sequence Detail 27811 C57BL/6J ±  kb
transcript ENSMUST00000113367 Ensembl | MGI Sequence Detail 2207 Not Applicable  
polypeptide ENSMUSP00000108994 Ensembl | MGI Sequence Detail 646 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site
    IPR011545 DEAD/DEAH box helicase domain
    IPR001650 Helicase, C-terminal
    IPR014001 Helicase superfamily 1/2, ATP-binding domain
    IPR004087 K Homology domain
    IPR004088 K Homology domain, type 1
    IPR036612 K Homology domain, type 1 superfamily
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR014014 RNA helicase, DEAD-box type, Q motif
Molecular
Reagents
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  • All nucleic 2
    cDNA 2

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Gene Ontology 1
    Phenotypes 13
  • Earliest
    J:12013 Russell LB, Definition of functional units in a small chromosomal segment of the mouse and its use in interpreting the nature of radiation-induced mutations. Mutat Res. 1971 Jan;11(1):107-23
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory