Mhrt MGI Mouse Gene Detail - MGI:3642848 - myosin heavy chain associated RNA transcript

Symbol

Mhrt
Name

myosin heavy chain associated RNA transcript
Synonyms

D830015G02Rik

Feature Type

lncRNA gene
IDs

MGI:3642848
NCBI Gene: 791403
Alliance

gene page
Transcription Start Sites

12 TSS

Sequence Map

Chr14:55206215-55211915 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 14, 28.01 cM
Mapping Data

1 experiment

SNPs within 2kb

223 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3642848	lncRNA gene	Chr14:55205795-55229058 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0003247	antisense lncRNA gene	Chr14:48953860-48961541 (+)
A/J	MGP_AJ_G0003223	antisense lncRNA gene	Chr14:47988107-47993789 (+)
AKR/J	MGP_AKRJ_G0003206	antisense lncRNA gene	Chr14:49742249-49747931 (+)
BALB/cJ	MGP_BALBcJ_G0003212	antisense lncRNA gene	Chr14:47964426-47970137 (+)
C3H/HeJ	MGP_C3HHeJ_G0003165	antisense lncRNA gene	Chr14:49427984-49433670 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0003354	antisense lncRNA gene	Chr14:51428582-51434252 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0002879	antisense lncRNA gene	Chr14:46399637-46405296 (+)
CAST/EiJ	MGP_CASTEiJ_G0003131	antisense lncRNA gene	Chr14:45666585-45672244 (+)
CBA/J	MGP_CBAJ_G0003162	antisense lncRNA gene	Chr14:52986998-52995349 (+)
DBA/2J	MGP_DBA2J_G0003167	antisense lncRNA gene	Chr14:47728792-47734564 (+)
FVB/NJ	MGP_FVBNJ_G0003186	antisense lncRNA gene	Chr14:47191751-47192805 (+)
LP/J	MGP_LPJ_G0003244	antisense lncRNA gene	Chr14:50018214-50024923 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0003175	antisense lncRNA gene	Chr14:52371596-52376931 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0003356	antisense lncRNA gene	Chr14:48913209-48920543 (+)
PWK/PhJ	MGP_PWKPhJ_G0003089	antisense lncRNA gene	Chr14:44266070-44271884 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0003035	antisense lncRNA gene	Chr14:44896741-44902416 (+)
WSB/EiJ	MGP_WSBEiJ_G0003165	antisense lncRNA gene	Chr14:49208254-49215025 (+)

Human Ortholog

MHRT, myosin heavy chain associated RNA transcript

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MHRT, myosin heavy chain associated RNA transcript
Synonyms

Myheart
Links

HGNC:51291

NCBI Gene ID: 104564225
Chr Location

chr14:23415450-23417595 (+) GRCh38

MGI Vertebrate Homology

Mhrt stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: MHRT
Gene Tree

Mhrt

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References

1 with disease annotations

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Phenotype Summary

11 phenotype references

All Mutations and Alleles

2
Chemically induced (other)

1
Transgenic

1
Genomic Mutations

2 involving Mhrt
Incidental Mutations

APF
Find Mice (IMSR)

0 strains or lines available

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All GO Annotations

2
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

736
Tissues

20
cDNA Data

4
Literature Summary

1

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

75
RefSeq

1
UniProt

1

Ensembl

ENSMUSG00000097652 (Evidence)
NCBI Gene

791403

			Length	Strain/Species	Flank
genomic	791403	NCBI Gene Model \| MGI Sequence Detail	5701	C57BL/6J	± kb
transcript	NR_033497	RefSeq \| MGI Sequence Detail	966	C57BL/6
polypeptide	Q8BWC8	UniProt \| EBI \| MGI Sequence Detail	162	Not Applicable

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UniProt

1 Sequence

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All nucleic 8

cDNA 4

Primer pair 2

Other 2

Microarray probesets 1

Summaries

All 23

Developmental Gene Expression 1

Diseases 1

Gene Ontology 1

Phenotypes 11
Earliest

J:82353 Schmitt JP, et al., Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban. Science. 2003 Feb 28;299(5611):1410-3
Latest

J:322344 Zhang QJ, et al., Matricellular Protein Cilp1 Promotes Myocardial Fibrosis in Response to Myocardial Infarction. Circ Res. 2021 Nov 12;129(11):1021-1035

TSS for Mhrt:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr125718	Chr14:55206129-55206140 (+)	-80 bp
Tssr125719	Chr14:55206208-55206232 (+)	5 bp
Tssr125720	Chr14:55206238-55206257 (+)	33 bp
Tssr125721	Chr14:55206258-55206269 (+)	49 bp
Tssr125722	Chr14:55206683-55206717 (+)	485 bp
Tssr125723	Chr14:55206752-55206759 (+)	541 bp
Tssr125724	Chr14:55206764-55206799 (+)	567 bp
Tssr125725	Chr14:55207624-55207640 (+)	1,417 bp
Tssr125726	Chr14:55207649-55207664 (+)	1,442 bp
Tssr125727	Chr14:55207682-55207691 (+)	1,472 bp
Tssr125728	Chr14:55208490-55208499 (+)	2,280 bp
Tssr125729	Chr14:55209364-55209368 (+)	3,151 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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