Mhrt Gene Detail

Summary

• Symbol
  Mhrt
• Name
  myosin heavy chain associated RNA transcript
• Synonyms
  D830015G02Rik

• Feature Type
  lncRNA gene
• IDs
  MGI:3642848
  NCBI Gene: 791403
• Alliance
  gene page
• Transcription Start Sites
  12 TSS

Location &
Maps

• Sequence Map
  Chr14:55206215-55211915 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 14, 28.01 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  223 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3642848	lncRNA gene	Chr14:55205795-55229058 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0003247	antisense lncRNA gene	Chr14:48953860-48961541 (+)
A/J	MGP_AJ_G0003223	antisense lncRNA gene	Chr14:47988107-47993789 (+)
AKR/J	MGP_AKRJ_G0003206	antisense lncRNA gene	Chr14:49742249-49747931 (+)
BALB/cJ	MGP_BALBcJ_G0003212	antisense lncRNA gene	Chr14:47964426-47970137 (+)
C3H/HeJ	MGP_C3HHeJ_G0003165	antisense lncRNA gene	Chr14:49427984-49433670 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0003354	antisense lncRNA gene	Chr14:51428582-51434252 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0002879	antisense lncRNA gene	Chr14:46399637-46405296 (+)
CAST/EiJ	MGP_CASTEiJ_G0003131	antisense lncRNA gene	Chr14:45666585-45672244 (+)
CBA/J	MGP_CBAJ_G0003162	antisense lncRNA gene	Chr14:52986998-52995349 (+)
DBA/2J	MGP_DBA2J_G0003167	antisense lncRNA gene	Chr14:47728792-47734564 (+)
FVB/NJ	MGP_FVBNJ_G0003186	antisense lncRNA gene	Chr14:47191751-47192805 (+)
LP/J	MGP_LPJ_G0003244	antisense lncRNA gene	Chr14:50018214-50024923 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0003175	antisense lncRNA gene	Chr14:52371596-52376931 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0003356	antisense lncRNA gene	Chr14:48913209-48920543 (+)
PWK/PhJ	MGP_PWKPhJ_G0003089	antisense lncRNA gene	Chr14:44266070-44271884 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0003035	antisense lncRNA gene	Chr14:44896741-44902416 (+)
WSB/EiJ	MGP_WSBEiJ_G0003165	antisense lncRNA gene	Chr14:49208254-49215025 (+)

Homology

• Human Ortholog
  MHRT, myosin heavy chain associated RNA transcript

• Vertebrate Orthologs
  1

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  MHRT, myosin heavy chain associated RNA transcript
  
• Synonyms
  Myheart
• Links
  HGNC:51291

  NCBI Gene ID: 104564225

  
  
• Chr Location
  chr14:23415450-23417595 (+)  GRCh38

---

• MGI Vertebrate Homology
  Mhrt stringent orthology
  1 human;1 mouse
  
• HCOP
  vertebrate homology predictions: MHRT
• Gene Tree
  Mhrt
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  11 phenotype references
  

• All Mutations and Alleles
  2
• Chemically induced (other)
  1
• Transgenic
  1
• Genomic Mutations
  2 involving Mhrt
• Incidental Mutations
  APF
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  736
• Tissues
  20
• cDNA Data
  4
• Literature Summary
  1

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  75
• RefSeq
  1
• UniProt
  1

• Ensembl
  ENSMUSG00000097652 (Evidence)
• NCBI Gene
  791403

Representative Sequences			Length	Strain/Species
genomic	791403	NCBI Gene Model | MGI Sequence Detail	5701	C57BL/6J
transcript	NR_033497	RefSeq | MGI Sequence Detail	966	C57BL/6
polypeptide	Q8BWC8	UniProt | EBI | MGI Sequence Detail	162	Not Applicable

Protein
Information

• UniProt
  1 Sequence

Molecular
Reagents

• All nucleic 8

  cDNA 4

  Primer pair 2

  Other 2

  
  

  Microarray probesets 1

References

• Summaries
  All 23

  Developmental Gene Expression 1

  Diseases 1

  Phenotypes 11
• Earliest
  J:82353 Schmitt JP, et al., Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban. Science. 2003 Feb 28;299(5611):1410-3
• Latest
  J:322344 Zhang QJ, et al., Matricellular Protein Cilp1 Promotes Myocardial Fibrosis in Response to Myocardial Infarction. Circ Res. 2021 Nov 12;129(11):1021-1035

TSS for Mhrt:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr125718	Chr14:55206129-55206140 (+)	-80 bp
Tssr125719	Chr14:55206208-55206232 (+)	5 bp
Tssr125720	Chr14:55206238-55206257 (+)	33 bp
Tssr125721	Chr14:55206258-55206269 (+)	49 bp
Tssr125722	Chr14:55206683-55206717 (+)	485 bp
Tssr125723	Chr14:55206752-55206759 (+)	541 bp
Tssr125724	Chr14:55206764-55206799 (+)	567 bp
Tssr125725	Chr14:55207624-55207640 (+)	1,417 bp
Tssr125726	Chr14:55207649-55207664 (+)	1,442 bp
Tssr125727	Chr14:55207682-55207691 (+)	1,472 bp
Tssr125728	Chr14:55208490-55208499 (+)	2,280 bp
Tssr125729	Chr14:55209364-55209368 (+)	3,151 bp