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Mhrt Gene Detail
Summary
  • Symbol
    Mhrt
  • Name
    myosin heavy chain associated RNA transcript
  • Synonyms
    D830015G02Rik
  • Feature Type
    lncRNA gene
  • IDs
    MGI:3642848
    NCBI Gene: 791403
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:55206244-55211806 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 28.01 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    116 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3642848
 lncRNA gene Chr14:55206104-55211920 (+)
129S1/SvImJ MGP_129S1SvImJ_G0003247
 antisense lncRNA gene Chr14:48953860-48961541 (+)
A/J MGP_AJ_G0003223
 antisense lncRNA gene Chr14:47988107-47993789 (+)
AKR/J MGP_AKRJ_G0003206
 antisense lncRNA gene Chr14:49742249-49747931 (+)
BALB/cJ MGP_BALBcJ_G0003212
 antisense lncRNA gene Chr14:47964426-47970137 (+)
C3H/HeJ MGP_C3HHeJ_G0003165
 antisense lncRNA gene Chr14:49427984-49433670 (+)
C57BL/6NJ MGP_C57BL6NJ_G0003354
 antisense lncRNA gene Chr14:51428582-51434252 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0002879
 antisense lncRNA gene Chr14:46399637-46405296 (+)
CAST/EiJ MGP_CASTEiJ_G0003131
 antisense lncRNA gene Chr14:45666585-45672244 (+)
CBA/J MGP_CBAJ_G0003162
 antisense lncRNA gene Chr14:52986998-52995349 (+)
DBA/2J MGP_DBA2J_G0003167
 antisense lncRNA gene Chr14:47728792-47734564 (+)
FVB/NJ MGP_FVBNJ_G0003186
 antisense lncRNA gene Chr14:47191751-47192805 (+)
LP/J MGP_LPJ_G0003244
 antisense lncRNA gene Chr14:50018214-50024923 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0003175
 antisense lncRNA gene Chr14:52371596-52376931 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0003356
 antisense lncRNA gene Chr14:48913209-48920543 (+)
PWK/PhJ MGP_PWKPhJ_G0003089
 antisense lncRNA gene Chr14:44266070-44271884 (+)
SPRET/EiJ MGP_SPRETEiJ_G0003035
 antisense lncRNA gene Chr14:44896741-44902416 (+)
WSB/EiJ MGP_WSBEiJ_G0003165
 antisense lncRNA gene Chr14:49208254-49215025 (+)



Homology
more
  • Human Ortholog
    MHRT, myosin heavy chain associated RNA transcript
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MHRT, myosin heavy chain associated RNA transcript
  • Synonyms
    Myheart
  • Links
    NCBI Gene ID: 104564225

  • Chr Location
    chr14:23415450-23417595 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    736
  • Tissues
    20
  • cDNA Data
    3
  • Literature Summary
    1
Sequences &
Gene Models
less
  • All Sequences
    39
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 791403 NCBI Gene Model | MGI Sequence Detail 5563 C57BL/6J ±  kb
transcript NR_033497 RefSeq | MGI Sequence Detail 828 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 7
    cDNA 3
    Primer pair 2
    Other 2

    Microarray probesets 1
References
more
  • Summaries
    All 12
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:213053 Han P, et al., A long noncoding RNA protects the heart from pathological hypertrophy. Nature. 2014 Oct 2;514(7520):102-106
  • Latest
    J:288294 Xu Y, et al., LncRNA-Mhrt regulates cardiac hypertrophy by modulating the miR-145a-5p/KLF4/myocardin axis. J Mol Cell Cardiol. 2020 Feb;139:47-61
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/26/2022
MGI 6.22 		The Jackson Laboratory