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Dnah7c Gene Detail
Summary
  • Symbol
    Dnah7c
  • Name
    dynein, axonemal, heavy chain 7C
  • Synonyms
    Dnahc7c
  • Feature Type
    protein coding gene
  • IDs
    MGI:3639762
    NCBI Gene: 100101919
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:46464752-46846636 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 24.00 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1623 from dbSNP Build 142
  • Strain Annotations
    5
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3639762
 protein coding gene Chr1:46464590-46846637 (+)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0015938
 protein coding gene Chr1:43606594-44190133 (+)
C3H/HeJ MGP_C3HHeJ_G0015770
 protein coding gene Chr1:45021881-45629225 (+)
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0015844
 protein coding gene Chr1:42663760-43220518 (+)
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0015135
 protein coding gene Chr1:43254319-43263967 (+)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    DNAH7, dynein axonemal heavy chain 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DNAH7, dynein axonemal heavy chain 7
  • Synonyms
    CILD50
  • Links
    NCBI Gene ID: 56171
    neXtProt AC: NX_Q8WXX0
    UniProt: Q8WXX0

  • Chr Location
    2q32.3; chr2:195737703-196068837 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human DNAH7 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    2
  • cDNA Data
    5
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000101337 Ensembl Gene Model | MGI Sequence Detail 381885 C57BL/6J ±  kb
transcript ENSMUST00000189749 Ensembl | MGI Sequence Detail 12207 Not Applicable  
polypeptide ENSMUSP00000140430 Ensembl | MGI Sequence Detail 4024 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR003593 AAA+ ATPase domain
    IPR026983 Dynein heavy chain
    IPR041589 Dynein heavy chain 3, AAA+ lid domain
    IPR043157 Dynein heavy chain, AAA1 domain, small subdomain
    IPR041466 Dynein heavy chain, AAA 5 extension domain
    IPR041658 Dynein heavy chain AAA lid domain
    IPR042219 Dynein heavy chain AAA lid domain superfamily
    IPR024317 Dynein heavy chain, AAA module D4
    IPR035706 Dynein heavy chain, ATP-binding dynein motor region
    IPR024743 Dynein heavy chain, coiled coil stalk
    IPR041228 Dynein heavy chain, C-terminal domain
    IPR043160 Dynein heavy chain, C-terminal domain, barrel region
    IPR042222 Dynein heavy chain, domain 2, N-terminal
    IPR035699 Dynein heavy chain, hydrolytic ATP-binding dynein motor region
    IPR013602 Dynein heavy chain, linker
    IPR042228 Dynein heavy chain, linker, subdomain 3
    IPR004273 Dynein heavy chain region D6 P-loop domain
    IPR018247 EF-Hand 1, calcium-binding site
    IPR002048 EF-hand domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5
References
more
  • Summaries
    All 17
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:208266 Dong F, et al., Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm. J Cell Biol. 2014 Jan 20;204(2):203-13
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory