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Krt74
Gene Detail
Symbol

Name
ID
Krt74
keratin 74
MGI:3629975
BioType Conflict
Synonyms
Kb37
Feature Type
protein coding gene
Genetic Map
Chromosome 15
57.01 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr15:101754259-101763504 bp, - strand
From NCBI annotation of GRCm38

  9246 bp   ±  kb flank

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Mouse Genome Browser
Vertebrate
homology
Gene Tree: Krt74
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Radiation induced(1) Targeted(4)
Genomic Mutations involving Krt74 (2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Krt74 interacts with 32 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process biological_process
Component intermediate filament, keratin filament
Function structural molecule activity
Expression
cDNA source data(1)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(2) cDNA(1) Other(1)
Other database
links
Ensembl Gene ModelENSMUSG00000067596 (Evidence)
Entrez Gene406222 (Evidence)
UniGene359153
DoTSDT.103569200
NIA Mouse Gene IndexU255767
International Mouse Knockout Project StatusKrt74
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 406222 NCBI Gene Model | MGI Sequence Detail 9246 C57BL/6J ±  kb
transcript NR_033444 RefSeq | MGI Sequence Detail 1589 Not Specified 
polypeptide Q6IFZ9 UniProt | EBI | MGI Sequence Detail 495 Not Applicable 

For the selected sequences
All sequences(12) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(97 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001664 Intermediate filament protein
InterPro IPR018039 Intermediate filament protein, conserved site
InterPro IPR003054 Type II keratin
Protein Ontology PR:000009489 keratin, type II cytoskeletal 74
Graphical View of Protein Domain Structure
References
(Earliest) J:109436 Schweizer J, et al., New consensus nomenclature for mammalian keratins. J Cell Biol. 2006 Jul 17;174(2):169-74
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(20)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory