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Krt74 Gene Detail
Summary
  • Symbol
    Krt74
  • Name
    keratin 74
  • Synonyms
    Kb37
Location & Maps
more
  • Sequence Map
    Chr15:101754259-101763504 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      9246 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 57.01 cM
  • Mapping Data
    1 experiment
Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    27 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Targeted
    5
  • Genomic Mutations
    4 involving Krt74
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
  • UniGene
Representative SequencesLengthStrain/SpeciesFlank
genomic 406222 NCBI Gene Model | MGI Sequence Detail 9246 C57BL/6J ±  kb
transcript NR_033444 RefSeq | MGI Sequence Detail 1589 Not Specified  
polypeptide Q6IFZ9 UniProt | EBI | MGI Sequence Detail 495 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    97 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000009489 keratin, type II cytoskeletal 74
  • InterPro Domains
    IPR001664 Intermediate filament protein
    IPR018039 Intermediate filament protein, conserved site
    IPR003054 Keratin, type II
    IPR032444 Keratin type II head
Molecular
Reagents
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  • All nucleic 2
    cDNA 1
    Other 1
References
more
  • Summaries
    All 20
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 2
    Phenotypes 27
  • Earliest
    J:109436 Schweizer J, et al., New consensus nomenclature for mammalian keratins. J Cell Biol. 2006 Jul 17;174(2):169-74
  • Latest
    J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory