Krt74
Gene Detail

Symbol

Name
ID

BioType Conflict

Krt74
keratin 74
MGI:3629975

Synonyms

Kb37

Feature Type

protein coding gene

Genetic Map

Chromosome 15
57.01 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr15:101754259-101763504 bp, - strand From NCBI annotation of GRCm38   9246 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

Gene Tree: Krt74

Mutations,
alleles, and
phenotypes

All mutations/alleles(5) : Radiation induced(1) Targeted(4)
Genomic Mutations involving Krt74 (2)
Incidental mutations (data from Mutagenetix , APF )
Phenotype Images(2)

Interactions

Krt74 interacts with 32 markers (Mir15a, Mir15b, Mir16-1, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (5 annotations)

Process	biological_process
Component	intermediate filament, keratin filament
Function	structural molecule activity

Expression

cDNA source data(1)
External Resources: GEO   Expression Atlas

Molecular
reagents

All nucleic(2) cDNA(1) Other(1)

Other database
links

Ensembl Gene Model	ENSMUSG00000067596 (Evidence)
Entrez Gene	406222 (Evidence)
UniGene	359153
DoTS	DT.103569200
NIA Mouse Gene Index	U255767
International Mouse Knockout Project Status	Krt74

Sequences

Length	Strain/Species
genomic	406222	NCBI Gene Model | MGI Sequence Detail	9246	C57BL/6J
transcript	NR_033444	RefSeq | MGI Sequence Detail	1589	Not Specified
polypeptide	Q6IFZ9	UniProt | EBI | MGI Sequence Detail	495	Not Applicable

All sequences(12) RefSeq(2) UniProt(1)

Polymorphisms

SNPs within 2kb(97 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR001664	Intermediate filament protein
InterPro	IPR018039	Intermediate filament protein, conserved site
InterPro	IPR003054	Type II keratin
Protein Ontology	PR:000009489	keratin, type II cytoskeletal 74

Graphical View of Protein Domain Structure

References

(Earliest) J:109436 Schweizer J, et al., New consensus nomenclature for mammalian keratins. J Cell Biol. 2006 Jul 17;174(2):169-74
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(20)