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Mir146b Gene Detail
Summary
  • Symbol
    Mir146b
  • Name
    microRNA 146b
  • Synonyms
    mir 146b, Mirn146b, mmu-mir-146b
  • Feature Type
    miRNA gene
  • IDs
    MGI:3629945
    NCBI Gene: 751550
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr19:46342762-46342870 bp, + strand
  • From miRBase annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 38.82 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    11 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3629945
miRNA gene Chr19:46342762-46342870 (+)
129S1/SvImJ MGP_129S1SvImJ_G0008450
miRNA gene Chr19:46024970-46025078 (+)
A/J MGP_AJ_G0008438
miRNA gene Chr19:43759440-43759548 (+)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0008425
miRNA gene Chr19:43818232-43818340 (+)
C3H/HeJ MGP_C3HHeJ_G0008368
miRNA gene Chr19:45345026-45345134 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008628
miRNA gene Chr19:47175002-47175110 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007646
miRNA gene Chr19:42997387-42997495 (+)
CAST/EiJ MGP_CASTEiJ_G0008225
miRNA gene Chr19:45143775-45143883 (+)
CBA/J MGP_CBAJ_G0008333
miRNA gene Chr19:49530248-49530356 (+)
DBA/2J MGP_DBA2J_G0008368
miRNA gene Chr19:43582409-43582517 (+)
FVB/NJ MGP_FVBNJ_G0008389
miRNA gene Chr19:43359591-43359699 (+)
LP/J MGP_LPJ_G0008453
miRNA gene Chr19:45934032-45934140 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0008353
miRNA gene Chr19:48873517-48873625 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008618
miRNA gene Chr19:45283778-45283882 (+)
PWK/PhJ MGP_PWKPhJ_G0008149
miRNA gene Chr19:43529540-43529648 (+)
SPRET/EiJ MGP_SPRETEiJ_G0008023
miRNA gene Chr19:43937884-43937992 (+)
WSB/EiJ MGP_WSBEiJ_G0008309
miRNA gene Chr19:45426925-45427033 (+)



Homology
more
  • Human Ortholog
    MIR146B, microRNA 146b
  • Human Ortholog
    MIR146B, microRNA 146b
    Orthology source: HGNC
  • Synonyms
    mir-146b, MIRN146B, miRNA146B
  • Links
    NCBI Gene ID: 574447

  • Chr Location
    chr10:102436512-102436584 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 751550 NCBI Gene Model | MGI Sequence Detail 109 C57BL/6J ±  kb
transcript NR_030468 RefSeq | MGI Sequence Detail 109 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 1
    Other 1
Other Database
Links
less
References
more
  • Summaries
    All 17
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 1
  • Earliest
    J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
  • Latest
    J:266124 Cho S, et al., Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b. Nat Commun. 2018 Jul 16;9(1):2757

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory