Mir490 Gene Detail

Summary

• Symbol
  Mir490
• Name
  microRNA 490
• Synonyms
  mir 490, Mirn490, mmu-mir-490

• Feature Type
  miRNA gene
• IDs
  MGI:3629662
  NCBI Gene: 735279
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr6:36398677-36398760 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 6, 15.48 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  34 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3629662	miRNA gene	Chr6:36398677-36398760 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0008895	miRNA gene	Chr6:34581845-34581928 (+)
A/J	MGP_AJ_G0008880	miRNA gene	Chr6:33095370-33095453 (+)
AKR/J	MGP_AKRJ_G0008870	miRNA gene	Chr6:34168414-34168497 (+)
BALB/cJ	MGP_BALBcJ_G0008868	miRNA gene	Chr6:33292289-33292372 (+)
C3H/HeJ	MGP_C3HHeJ_G0008807	miRNA gene	Chr6:34171673-34171756 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0009097	miRNA gene	Chr6:35458596-35458679 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0008017	miRNA gene	Chr6:31067141-31067224 (+)
CAST/EiJ	MGP_CASTEiJ_G0008650	miRNA gene	Chr6:33982414-33982497 (+)
CBA/J	MGP_CBAJ_G0008774	miRNA gene	Chr6:36846719-36846802 (+)
DBA/2J	MGP_DBA2J_G0008806	miRNA gene	Chr6:32941019-32941102 (+)
FVB/NJ	MGP_FVBNJ_G0008824	miRNA gene	Chr6:32741425-32741508 (+)
LP/J	MGP_LPJ_G0008899	miRNA gene	Chr6:34702632-34702715 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0008789	miRNA gene	Chr6:39212033-39212116 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0009074	miRNA gene	Chr6:34078884-34078967 (+)
PWK/PhJ	MGP_PWKPhJ_G0008577	miRNA gene	Chr6:32545063-32545146 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0008421	miRNA gene	Chr6:33759628-33759711 (+)
WSB/EiJ	MGP_WSBEiJ_G0008746	miRNA gene	Chr6:34011938-34012021 (+)

Homology

• Human Ortholog
  MIR490, microRNA 490

• Vertebrate Orthologs
  1

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  MIR490, microRNA 490
  
• Synonyms
  hsa-mir-490, miR-490, MIRN490
• Links
  HGNC:32075

  NCBI Gene ID: 574443

  
  
• Chr Location
  chr7:136903167-136903294 (+)  GRCh38

---

• MGI Vertebrate Homology
  Mir490 stringent orthology
  1 human;1 mouse
  
• HCOP
  vertebrate homology predictions: MIR490
• Gene Tree
  Mir490
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  2
• Endonuclease-mediated
  1
• Targeted
  1
• Find Mice (IMSR)
  1 strains or lines available

Expression

• Assay Results
  802
• Tissues
  8
• Literature Summary
  2

Images

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  23
• RefSeq
  1

• Ensembl
  ENSMUSG00000070075 (Evidence)
• NCBI Gene
  735279

Representative Sequences			Length	Strain/Species
genomic	735279	NCBI Gene Model | MGI Sequence Detail	84	C57BL/6J
transcript	NR_030524	RefSeq | MGI Sequence Detail	84	C57BL/6

Molecular
Reagents

• All nucleic 1

  Other 1

Other Database
Links

miRBase

MI0005002

References

• Summaries
  All 10

  Developmental Gene Expression 2

  Phenotypes 2
• Earliest
  J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
• Latest
  J:219767 Shen J, et al., Epigenetic silencing of miR-490-3p reactivates the chromatin remodeler SMARCD1 to promote Helicobacter pylori-induced gastric carcinogenesis. Cancer Res. 2015 Feb 15;75(4):754-65