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Mir338 Gene Detail
Summary
  • Symbol
    Mir338
  • Name
    microRNA 338
  • Synonyms
    mir 338, Mirn338, mmu-mir-338
  • Feature Type
    miRNA gene
  • IDs
    MGI:3619352
    NCBI Gene: 723844
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr11:119905591-119905688 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 83.96 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    10 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3619352
 miRNA gene Chr11:119905591-119905688 (-)
129S1/SvImJ MGP_129S1SvImJ_G0007900
 miRNA gene Chr11:124446761-124446858 (-)
A/J MGP_AJ_G0007894
 miRNA gene Chr11:118917165-118917262 (-)
AKR/J MGP_AKRJ_G0007869
 miRNA gene Chr11:122496591-122496688 (-)
BALB/cJ MGP_BALBcJ_G0007873
 miRNA gene Chr11:119272731-119272828 (-)
C3H/HeJ MGP_C3HHeJ_G0007819
 miRNA gene Chr11:122817263-122817360 (-)
C57BL/6NJ MGP_C57BL6NJ_G0008053
 miRNA gene Chr11:128213011-128213108 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0007189
 miRNA gene Chr11:115919979-115920068 (-)
CAST/EiJ MGP_CASTEiJ_G0007712
 miRNA gene Chr11:124293899-124293996 (-)
CBA/J MGP_CBAJ_G0007790
 miRNA gene Chr11:133227964-133228061 (-)
DBA/2J MGP_DBA2J_G0007825
 miRNA gene Chr11:118282958-118283055 (-)
FVB/NJ MGP_FVBNJ_G0007844
 miRNA gene Chr11:117971816-117971913 (-)
LP/J MGP_LPJ_G0007903
 miRNA gene Chr11:124755557-124755654 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0007814
 miRNA gene Chr11:132096097-132096194 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0008047
 miRNA gene Chr11:123177837-123177934 (-)
PWK/PhJ MGP_PWKPhJ_G0007638
 miRNA gene Chr11:119709437-119709534 (-)
SPRET/EiJ MGP_SPRETEiJ_G0007534
 miRNA gene Chr11:122943928-122944025 (-)
WSB/EiJ MGP_WSBEiJ_G0007780
 miRNA gene Chr11:123172911-123173008 (-)



Homology
more
  • Human Ortholog
    MIR338, microRNA 338
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR338, microRNA 338
  • Synonyms
    hsa-mir-338, mir-338, MIRN338
  • Links
    NCBI Gene ID: 442906

  • Chr Location
    chr17:81125883-81125949 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit incrased trabecular bone volume and thickness, decreased osteoclast cell number, and resistance to ovariectomy-induced osteoporosis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    721
  • Tissues
    15
  • Literature Summary
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      23
    • RefSeq
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 723844 NCBI Gene Model | MGI Sequence Detail 98 C57BL/6J ±  kb
    transcript NR_029767 RefSeq | MGI Sequence Detail 98 C57BL/6  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 6
      Primer pair 2
      Other 4
    Other Database
    Links
    less
    miRBase MI0000619
    References
    more
    • Summaries
      All 29
      Developmental Gene Expression 8
      Gene Ontology 7
      Phenotypes 5
    • Earliest
      J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
    • Latest
      J:339746 Jin R, et al., Inhibition of miR338 rescues cleidocranial dysplasia in Runx2 mutant mice partially via the Hif1a-Vegfa axis. Exp Mol Med. 2023 Jan;55(1):69-80
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory