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Mir33 Gene Detail
Summary
  • Symbol
    Mir33
  • Name
    microRNA 33
  • Synonyms
    mir 33, Mirn33, mmu-mir-33
  • Feature Type
    miRNA gene
  • IDs
    MGI:3619343
    NCBI Gene: 723897
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr15:82198122-82198190 bp, + strand
  • From miRBase annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 38.54 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    15 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3619343
miRNA gene Chr15:82198122-82198190 (.)
129S1/SvImJ MGP_129S1SvImJ_G0008200
miRNA gene Chr15:82694081-82694149 (+)
A/J MGP_AJ_G0008190
miRNA gene Chr15:79765353-79765421 (+)
AKR/J MGP_AKRJ_G0008171
miRNA gene Chr15:81974188-81974256 (+)
BALB/cJ MGP_BALBcJ_G0008173
miRNA gene Chr15:79815397-79815465 (+)
C3H/HeJ MGP_C3HHeJ_G0008115
miRNA gene Chr15:81992724-81992792 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008366
miRNA gene Chr15:85930454-85930522 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007444
miRNA gene Chr15:76206121-76206189 (+)
CAST/EiJ MGP_CASTEiJ_G0007990
miRNA gene Chr15:82789567-82789635 (+)
CBA/J MGP_CBAJ_G0008084
miRNA gene Chr15:88618280-88618348 (+)
DBA/2J MGP_DBA2J_G0008119
miRNA gene Chr15:79238743-79238811 (+)
FVB/NJ MGP_FVBNJ_G0008144
miRNA gene Chr15:78298609-78298677 (+)
LP/J MGP_LPJ_G0008199
miRNA gene Chr15:82837165-82837233 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0008109
miRNA gene Chr15:93528877-93528945 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008360
miRNA gene Chr15:82087817-82087885 (+)
PWK/PhJ MGP_PWKPhJ_G0007913
miRNA gene Chr15:79291667-79291735 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007803
miRNA gene Chr15:81868188-81868256 (+)
WSB/EiJ MGP_WSBEiJ_G0008069
miRNA gene Chr15:82502339-82502407 (+)



Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    25 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Targeted
    2
  • Genomic Mutations
    3 involving Mir33
  • Find Mice (IMSR)
Mice homozygous for a null mutation display increased cellular cholesterol efflux and elevated circulating total and HDL cholesterol levels.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • Literature Summary
Interactions
less
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 723897 NCBI Gene Model | MGI Sequence Detail 69 C57BL/6J ±  kb
transcript NR_029804 RefSeq | MGI Sequence Detail 69 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 1
    Other 1
Other Database
Links
less
References
more
  • Summaries
    All 51
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 1
    Phenotypes 25
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:265266 Baba O, et al., MicroRNA 33 Regulates the Population of Peripheral Inflammatory Ly6C(high) Monocytes through Dual Pathways. Mol Cell Biol. 2018 Jul 15;38(14)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory