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Mir33 Gene Detail
Summary
  • Symbol
    Mir33
  • Name
    microRNA 33
  • Synonyms
    mir 33, Mirn33, mmu-mir-33
  • Feature Type
    miRNA gene
  • IDs
    MGI:3619343
    NCBI Gene: 723897
Location & Maps
more
  • Sequence Map
    Chr15:82198122-82198190 bp, + strand
  • From miRBase annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      69 bp   ±  kb flank

  • Genome Browsers
Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    21 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    3 involving Mir33
Mice homozygous for a null mutation display increased cellular cholesterol efflux and elevated circulating total and HDL cholesterol levels.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • Literature Summary
Interactions
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Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 723897 NCBI Gene Model | MGI Sequence Detail 69 C57BL/6J ±  kb
transcript NR_029804 RefSeq | MGI Sequence Detail 69 C57BL/6  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    15 from dbSNP Build 137
Molecular
Reagents
less
  • All nucleic 1
    Other 1
Other Database
Links
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References
more
  • Summaries
    All 14
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 1
    Phenotypes 21
  • Earliest
    J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
  • Latest
    J:227051 Kim J, et al., microRNA-33 Regulates ApoE Lipidation and Amyloid-beta Metabolism in the Brain. J Neurosci. 2015 Nov 4;35(44):14717-26

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory