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Mir10a
Gene Detail
Symbol

Name
ID
Mir10a
microRNA 10a
MGI:3619064
Synonyms
MicroRNA-10a, mir 10a, miR-10a, Mirn10a, mmu-mir-10a
Feature Type
miRNA gene
Genetic Map
Chromosome 11
59.83 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:96317165-96317274 bp, + strand
From miRBase annotation of GRCm38

  110 bp   ±  kb flank

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Mouse Genome Browser
Vertebrate
homology
Gene Tree: Mir10a
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Targeted(7)
Genomic Mutations involving Mir10a (4)
 
Mice homozygous for a targeted deletion are viable with no observed pathologies. Mice homozygous for a knock-out allele exhibit increased frequency with of high-grade dysplasia and higher incidence of tubule-villous adenomas in Apcmin heterozygotes.
 
Interactions
Mir10a interacts with 5438 markers (0610030E20Rik, 0610040J01Rik, 1110002E22Rik, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process cellular response to inorganic substance, cellular response to lipopolysaccharide, ...
Expression
Literature Summary: (8 records)
Data Summary: Results (7)    Tissues (5)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 3
RT-PCR 4
Other mouse links: GEO   Expression Atlas
Molecular
reagents
All nucleic(3) Primer pair(1) Other(2)
Other database
links
Ensembl Gene Model ENSMUSG00000065519 (Evidence)
Entrez Gene 723893 (Evidence)
miRBase MI0000685
International Mouse Phenotyping Consortium Status Mir10a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 723893 NCBI Gene Model | MGI Sequence Detail 110 C57BL/6J ±  kb
transcript NR_029784 RefSeq | MGI Sequence Detail 110 C57BL/6 

For the selected sequences
All sequences(5) RefSeq(1)
Polymorphisms
SNPs within 2kb(6 from dbSNP Build 137)
References
(Earliest) J:93952 Mansfield JH, et al., MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression. Nat Genet. 2004 Oct;36(10):1079-83
(Latest) J:208428 Chu JY, et al., Dicer function is required in the metanephric mesenchyme for early kidney development. Am J Physiol Renal Physiol. 2014 Apr;306(7):F764-72
All references(24)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory