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Mir219a-2 Gene Detail
Summary
  • Symbol
    Mir219a-2
  • Name
    microRNA 219a-2
  • Synonyms
    mir 219-2, Mirn219-2, mmu-mir-219-2, mmu-mir-219a-2
  • Feature Type
    miRNA gene
  • IDs
    MGI:3618754
    NCBI Gene: 723904
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:29735643-29735739 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 20.72 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    12 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3618754
miRNA gene Chr2:29735643-29735739 (-)
129S1/SvImJ MGP_129S1SvImJ_G0008523
miRNA gene Chr2:28017458-28017554 (-)
A/J MGP_AJ_G0008511
miRNA gene Chr2:26917632-26917728 (-)
AKR/J MGP_AKRJ_G0008496
miRNA gene Chr2:27824697-27824793 (-)
BALB/cJ MGP_BALBcJ_G0008500
miRNA gene Chr2:27049817-27049913 (-)
C3H/HeJ MGP_C3HHeJ_G0008439
miRNA gene Chr2:27751174-27751270 (-)
C57BL/6NJ MGP_C57BL6NJ_G0008707
miRNA gene Chr2:28926715-28926811 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0007695
miRNA gene Chr2:25707605-25707701 (-)
CAST/EiJ MGP_CASTEiJ_G0008298
miRNA gene Chr2:27642066-27642162 (-)
CBA/J MGP_CBAJ_G0008404
miRNA gene Chr2:29927377-29927473 (-)
DBA/2J MGP_DBA2J_G0008442
miRNA gene Chr2:26714019-26714115 (-)
FVB/NJ MGP_FVBNJ_G0008460
miRNA gene Chr2:26517263-26517359 (-)
LP/J MGP_LPJ_G0008530
miRNA gene Chr2:27935985-27936081 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0008422
miRNA gene Chr2:29851994-29852090 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0008695
miRNA gene Chr2:27749791-27749887 (-)
PWK/PhJ MGP_PWKPhJ_G0008225
miRNA gene Chr2:26542498-26542594 (-)
SPRET/EiJ MGP_SPRETEiJ_G0008084
miRNA gene Chr2:27829265-27829361 (-)
WSB/EiJ MGP_WSBEiJ_G0008384
miRNA gene Chr2:27864510-27864606 (-)



Homology
more
  • Human Ortholog
    MIR219A2, microRNA 219a-2
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR219A2, microRNA 219a-2
  • Synonyms
    hsa-mir-219a-2, MIR219-2, mir-219a-2, MIRN219-2
  • Links
    NCBI Gene ID: 407003

  • Chr Location
    chr9:128392618-128392714 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotype references
Mice homozygous for a targeted deletion are viable with no observed pathologies.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 723904 NCBI Gene Model | MGI Sequence Detail 97 C57BL/6J ±  kb
transcript NR_029838 RefSeq | MGI Sequence Detail 97 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 4
    Primer pair 2
    Other 2
Other Database
Links
less
References
more
  • Summaries
    All 20
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
  • Latest
    J:240024 Wang H, et al., miR-219 Cooperates with miR-338 in Myelination and Promotes Myelin Repair in the CNS. Dev Cell. 2017 Mar 27;40(6):566-582.e5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/07/2021
MGI 6.17
The Jackson Laboratory