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Mir128-2 Gene Detail
Summary
  • Symbol
    Mir128-2
  • Name
    microRNA 128-2
  • Synonyms
    mir 128b, mir-128b, Mirn128-2, Mirn128b, mmu-mir-128-2, mmu-mir-128b
Location &
Maps
more
  • Sequence Map
    Chr9:111947704-111947779 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 62.46 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    81 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3618709
 miRNA gene Chr9:111947704-111947779 (-)
129S1/SvImJ ENSMUSG00200045585
 miRNA gene Chr9:109041648-109041723 (-)
A/J ENSMUSG00195045614
 miRNA gene Chr9:108365741-108365816 (-)
AKR/J ENSMUSG00220032044
 miRNA gene Chr9:108674157-108674232 (-)
BALB/cJ ENSMUSG00180036080
 miRNA gene Chr9:108793346-108793421 (-)
C3H/HeJ ENSMUSG00175046513
 miRNA gene Chr9:109009106-109009181 (-)
C57BL/6NJ ENSMUSG00215041420
 miRNA gene Chr9:108886324-108886399 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0008303
 miRNA gene Chr9:107386257-107386332 (-)
CAST/EiJ ENSTCUG00005036652
 miRNA gene Chr9:108686459-108686534 (-)
CBA/J ENSMUSG00210045357
 miRNA gene Chr9:108721146-108721221 (-)
DBA/2J ENSMUSG00185044638
 miRNA gene Chr9:109056989-109057064 (-)
FVB/NJ ENSMUSG00205050304
 miRNA gene Chr9:109009483-109009558 (-)
JF1/MsJ ENSUMUG00000055672
 miRNA gene Chr9:108817856-108817931 (-)
LP/J ENSMUSG00230050536
 miRNA gene Chr9:109173643-109173718 (-)
NOD/ShiLtJ ENSMUSG00190050933
 miRNA gene Chr9:108644629-108644704 (-)
NZO/HlLtJ ENSMUSG00225024670
 miRNA gene Chr9:109427171-109427246 (-)
PWK/PhJ ENSLUMG00010045685
 miRNA gene Chr9:108836029-108836104 (-)
SPRET/EiJ ENSMSPG00010048325
 miRNA gene Chr9:110642019-110642094 (-)
WSB/EiJ ENSIUOG00005048774
 miRNA gene Chr9:108117794-108117869 (-)



Homology
more
  • Human Ortholog
    MIR128-2, microRNA 128-2
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR128-2, microRNA 128-2
  • Synonyms
    mir-128-2, mir-128b, MIR128B, MIRN128-2, MIRN128B
  • Links
    NCBI Gene ID: 406916

  • Chr Location
    chr3:35744476-35744559 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 3 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit increased vertical activity, juvenile hyperactivity that progresses rapidly to severe seizures, and premature death.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    662
  • Tissues
    39
  • Literature Summary
    13
Sequences &
Gene Models
less
  • All Sequences
    24
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 723815 NCBI Gene Model | MGI Sequence Detail 76 C57BL/6J ±  kb
transcript NR_029823 RefSeq | MGI Sequence Detail 76 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 8
    Primer pair 3
    Other 5
Other Database
Links
less
miRBase MI0000726
References
more
  • Summaries
    All 32
    Developmental Gene Expression 13
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:84907 Lagos-Quintana M, et al., Identification of tissue-specific microRNAs from mouse. Curr Biol. 2002 Apr 30;12(9):735-9
  • Latest
    J:357554 Todorov H, et al., Stage-specific expression patterns and co-targeting relationships among miRNAs in the developing mouse cerebral cortex. Commun Biol. 2024 Oct 22;7(1):1366
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory