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Mir128-2 Gene Detail
Summary
  • Symbol
    Mir128-2
  • Name
    microRNA 128-2
  • Synonyms
    mir 128b, mir-128b, Mirn128-2, Mirn128b, mmu-mir-128-2, mmu-mir-128b
  • Feature Type
    miRNA gene
  • IDs
    MGI:3618709
    NCBI Gene: 723815
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr9:112118636-112118711 bp, - strand
  • From miRBase annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 62.46 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    8 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3618709
miRNA gene Chr9:112118636-112118711 (-)
129S1/SvImJ MGP_129S1SvImJ_G0009244
miRNA gene Chr9:114381691-114381766 (-)
A/J MGP_AJ_G0009225
miRNA gene Chr9:110181513-110181588 (-)
AKR/J MGP_AKRJ_G0009214
miRNA gene Chr9:112949562-112949637 (-)
BALB/cJ MGP_BALBcJ_G0009209
miRNA gene Chr9:109969339-109969414 (-)
C3H/HeJ MGP_C3HHeJ_G0009150
miRNA gene Chr9:113455285-113455360 (-)
C57BL/6NJ MGP_C57BL6NJ_G0009451
miRNA gene Chr9:117514419-117514494 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0008303
miRNA gene Chr9:107386257-107386332 (-)
CAST/EiJ MGP_CASTEiJ_G0008980
miRNA gene Chr9:113272350-113272425 (-)
CBA/J MGP_CBAJ_G0009115
miRNA gene Chr9:121856134-121856209 (-)
DBA/2J MGP_DBA2J_G0009145
miRNA gene Chr9:109639811-109639886 (-)
FVB/NJ MGP_FVBNJ_G0009163
miRNA gene Chr9:108475895-108475970 (-)
LP/J MGP_LPJ_G0009242
miRNA gene Chr9:114679717-114679792 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0009129
miRNA gene Chr9:123120065-123120140 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0009421
miRNA gene Chr9:113294049-113294124 (-)
PWK/PhJ MGP_PWKPhJ_G0008905
miRNA gene Chr9:109895818-109895893 (-)
SPRET/EiJ MGP_SPRETEiJ_G0008744
miRNA gene Chr9:113413937-113414012 (-)
WSB/EiJ MGP_WSBEiJ_G0009074
miRNA gene Chr9:113176573-113176648 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 3 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit increased vertical activity, juvenile hyperactivity that progresses rapidly to severe seizures, and premature death.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
Interactions
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Sequences &
Gene Models
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  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 723815 NCBI Gene Model | MGI Sequence Detail 76 C57BL/6J ±  kb
transcript NR_029823 RefSeq | MGI Sequence Detail 76 C57BL/6  
For the selected sequence
Molecular
Reagents
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  • All nucleic 2
    Other 2
Other Database
Links
less
References
more
  • Summaries
    All 20
    Developmental Gene Expression 8
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:101078 Smirnova L, et al., Regulation of miRNA expression during neural cell specification. Eur J Neurosci. 2005 Mar;21(6):1469-77
  • Latest
    J:257896 Huang W, et al., Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration. Nat Commun. 2018 Feb 16;9(1):700

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory