About   Help   FAQ
Doxl2 Gene Detail
Summary
  • Symbol
    Doxl2
  • Name
    diamine oxidase-like protein 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:3618290
    NCBI Gene: 243376
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:48974963-48978746 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 23.82 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    35 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3618290
protein coding gene Chr6:48974812-48978746 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030717
protein coding gene Chr6:47957693-47961476 (+)
A/J MGP_AJ_G0030688
protein coding gene Chr6:45767817-45771601 (+)
AKR/J MGP_AKRJ_G0030613
protein coding gene Chr6:47383225-47387008 (+)
BALB/cJ MGP_BALBcJ_G0030698
protein coding gene Chr6:46108771-46112554 (+)
C3H/HeJ MGP_C3HHeJ_G0030411
protein coding gene Chr6:47384103-47387886 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031153
protein coding gene Chr6:49086652-49090435 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028360
protein coding gene Chr6:43380930-43384701 (+)
CAST/EiJ MGP_CASTEiJ_G0029815
protein coding gene Chr6:47113789-47117585 (+)
CBA/J MGP_CBAJ_G0030386
protein coding gene Chr6:51122560-51126343 (+)
DBA/2J MGP_DBA2J_G0030535
protein coding gene Chr6:45683957-45687740 (+)
FVB/NJ MGP_FVBNJ_G0030487
protein coding gene Chr6:45318276-45322059 (+)
LP/J MGP_LPJ_G0030620
protein coding gene Chr6:47938357-47942140 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030521
protein coding gene Chr6:53899187-53902971 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031182
protein coding gene Chr6:47243654-47247437 (+)
PWK/PhJ MGP_PWKPhJ_G0029527
protein coding gene Chr6:45225141-45228983 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029363
protein coding gene Chr6:46591490-46595292 (+)
WSB/EiJ MGP_WSBEiJ_G0029892
protein coding gene Chr6:47247740-47252188 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000068536 Ensembl Gene Model | MGI Sequence Detail 3784 C57BL/6J ±  kb
transcript ENSMUST00000184917 Ensembl | MGI Sequence Detail 2468 Not Applicable  
polypeptide ENSMUSP00000139012 Ensembl | MGI Sequence Detail 723 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • EC
  • InterPro Domains
    IPR000269 Copper amine oxidase
    IPR015798 Copper amine oxidase, catalytic domain
    IPR036460 Copper amine oxidase, catalytic domain superfamily
    IPR015800 Copper amine oxidase, N2-terminal
    IPR015802 Copper amine oxidase, N3-terminal
    IPR016182 Copper amine oxidase, N-terminal
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 1
References
more
  • Summaries
    All 15
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:86672 Lundwall A, et al., Molecular cloning of complementary DNA encoding mouse seminal vesicle-secreted protein SVS I and demonstration of homology with copper amine oxidases. Biol Reprod. 2003 Dec;69(6):1923-30
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/13/2019
MGI 6.14
The Jackson Laboratory