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Mir378a Gene Detail
Summary
  • Symbol
    Mir378a
  • Name
    microRNA 378a
  • Synonyms
    Mirn378, mmu-mir-378, mmu-mir-378a
  • Feature Type
    miRNA gene
  • IDs
    MGI:3617791
    NCBI Gene: 723889
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr18:61397835-61397900 bp, - strand
  • From miRBase annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 34.62 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    14 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3617791
miRNA gene Chr18:61397835-61397900 (-)
129S1/SvImJ MGP_129S1SvImJ_G0008394
miRNA gene Chr18:61281253-61281318 (-)
A/J MGP_AJ_G0008383
miRNA gene Chr18:58648706-58648771 (-)
AKR/J MGP_AKRJ_G0008367
miRNA gene Chr18:60263943-60264008 (-)
BALB/cJ MGP_BALBcJ_G0008368
miRNA gene Chr18:58776309-58776374 (-)
C3H/HeJ MGP_C3HHeJ_G0008313
miRNA gene Chr18:60495968-60496033 (-)
C57BL/6NJ MGP_C57BL6NJ_G0008569
miRNA gene Chr18:62944136-62944201 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0007602
miRNA gene Chr18:58193492-58193557 (-)
CAST/EiJ MGP_CASTEiJ_G0008175
miRNA gene Chr18:60369284-60369349 (-)
CBA/J MGP_CBAJ_G0008279
miRNA gene Chr18:64963242-64963307 (-)
DBA/2J MGP_DBA2J_G0008311
miRNA gene Chr18:58315119-58315184 (-)
FVB/NJ MGP_FVBNJ_G0008333
miRNA gene Chr18:57727233-57727298 (-)
LP/J MGP_LPJ_G0008396
miRNA gene Chr18:61136832-61136897 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0008299
miRNA gene Chr18:66570870-66570935 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0008558
miRNA gene Chr18:60459287-60459352 (-)
PWK/PhJ MGP_PWKPhJ_G0008097
miRNA gene Chr18:58547708-58547773 (-)
SPRET/EiJ MGP_SPRETEiJ_G0007974
miRNA gene Chr18:60692620-60692685 (-)
WSB/EiJ MGP_WSBEiJ_G0008257
miRNA gene Chr18:60324986-60325051 (-)



Homology
more
  • Human Ortholog
    MIR378A, microRNA 378a
  • Human Ortholog
    MIR378A, microRNA 378a
    Orthology source: HGNC
  • Synonyms
    hsa-mir-378, hsa-mir-378a, MIR378, MIRN378, miRNA378
  • Links
    NCBI Gene ID: 494327

  • Chr Location
    chr5:149732825-149732890 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    1 images
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit resistance to diet-induced obesity with increased energy expenditure and reduced adipose.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Literature Summary
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 723889 NCBI Gene Model | MGI Sequence Detail 66 C57BL/6J ±  kb
transcript NR_029879 RefSeq | MGI Sequence Detail 66 C57BL/6  
For the selected sequence
Molecular
Reagents
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  • All nucleic 1
    Other 1
Other Database
Links
less
References
more
  • Summaries
    All 33
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:84906 Dostie J, et al., Numerous microRNPs in neuronal cells containing novel microRNAs. (Erratum: RNA 2003;9(5):631-2). RNA. 2003 Feb;9(2):180-6
  • Latest
    J:273633 Nagai T, et al., MicroRNAs control eyelid development through regulating Wnt signaling. Dev Dyn. 2019 Mar;248(3):201-210

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory