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Tagap
Gene Detail
Symbol

Name
ID
Tagap
T cell activation Rho GTPase activating protein
MGI:3615484
Feature Type
protein coding gene
Genetic Map
Chromosome 17
4.82 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr17:7926000-7934897 bp, + strand
From VEGA annotation of GRCm38

  8898 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:44943  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: TAGAP
Gene Tree: Tagap

Human
homologs
TAGAP, T-cell activation RhoGTPase activating protein
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 117289
neXtProt AC: NX_Q8N103

Human Synonyms: ARHGAP47, FKSG15, IDDM21, TAGAP1

Human Chr (Location): 6q25.3; chr6:159034468-159045152 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from APF , CvDC )
Interactions
Tagap interacts with 191 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (2 annotations)
Process signal transduction
Function guanyl-nucleotide exchange factor activity
Expression
cDNA source data(3)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase tagap    NEW 
Molecular
reagents
All nucleic(3) cDNA(3)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000034757 (Evidence)
Ensembl Gene Model ENSMUSG00000033450 (Evidence)
Entrez Gene 72536 (Evidence)
DoTS DT.531149
Consensus CDS Project CCDS28379.1
International Mouse Phenotyping Consortium Status Tagap
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034757 VEGA Gene Model | MGI Sequence Detail 8898 C57BL/6J ±  kb
transcript OTTMUST00000088332 VEGA | MGI Sequence Detail 3076 Not Applicable 
polypeptide OTTMUSP00000048122 VEGA | MGI Sequence Detail 714 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(87 from dbSNP Build 137)    SNPs within 2kb including multiple locations(171)
Protein-related
information
ResourceIDDescription
InterPro IPR000198 Rho GTPase-activating protein domain
InterPro IPR008936 Rho GTPase activation protein
Protein Ontology PR:000016038 T-cell activation Rho GTPase-activating protein
References
(Earliest) J:100859 Bauer H, et al., The t complex-encoded GTPase-activating protein Tagap1 acts as a transmission ratio distorter in mice. Nat Genet. 2005 Sep;37(9):969-73
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(20)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory