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Ano3 Gene Detail
Summary
  • Symbol
    Ano3
  • Name
    anoctamin 3
  • Synonyms
    B230324K02Rik, Tmem16c
  • Feature Type
    protein coding gene
  • IDs
    MGI:3613666
    NCBI Gene: 228432
Location & Maps
more
  • Sequence Map
    Chr2:110655201-110950923 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      295723 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    ANO3, anoctamin 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ANO3, anoctamin 3
    Orthology source: HomoloGene
  • Synonyms
    C11orf25, DYT23, DYT24, GENX-3947, TMEM16C
  • Links
    NCBI Gene ID: 63982
    neXtProt AC: NX_Q9BYT9

  • Chr Location
    11p14.2; chr11:26188821-26668409 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 57147
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: ANO3
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human ANO3 associations

Human Disease Mouse Models
       Dystonia 24; DYT24   OMIM: 615034
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    3 involving Ano3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015134 VEGA Gene Model | MGI Sequence Detail 295723 C57BL/6J ±  kb
transcript OTTMUST00000035936 VEGA | MGI Sequence Detail 6705 Not Applicable  
polypeptide OTTMUSP00000016132 VEGA | MGI Sequence Detail 981 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    2200 from dbSNP Build 137
Protein
Information
less
Molecular
Reagents
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  • All nucleic 3
    cDNA 3

    Microarray probesets 4
Other
Accession IDs
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MGI:2139060, MGI:3045304
References
more
  • Summaries
    All 26
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:138798 Rock JR, et al., Expression of TMEM16 paralogs during murine embryogenesis. Dev Dyn. 2008 Sep;237(9):2566-74
  • Latest
    J:221155 Quintens R, et al., Identification of novel radiation-induced p53-dependent transcripts extensively regulated during mouse brain development. Biol Open. 2015;4(3):331-44

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory