About   Help   FAQ
Ano3 Gene Detail
Summary
  • Symbol
    Ano3
  • Name
    anoctamin 3
  • Synonyms
    B230324K02Rik, Tmem16c
  • Feature Type
    protein coding gene
  • IDs
    MGI:3613666
    NCBI Gene: 228432
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:110655201-110950404 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 56.75 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2157 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3613666
protein coding gene Chr2:110655201-110950923 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026247
protein coding gene Chr2:113011005-113323537 (-)
A/J MGP_AJ_G0026208
protein coding gene Chr2:108292823-108596763 (-)
AKR/J MGP_AKRJ_G0026188
protein coding gene Chr2:111334593-111643665 (-)
BALB/cJ MGP_BALBcJ_G0026218
protein coding gene Chr2:108589934-108888767 (-)
C3H/HeJ MGP_C3HHeJ_G0025967
protein coding gene Chr2:111613265-111921888 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026669
protein coding gene Chr2:116700166-117035566 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024054
protein coding gene Chr2:103780800-104066351 (-)
CAST/EiJ MGP_CASTEiJ_G0025432
protein coding gene Chr2:112100976-112413395 (-)
CBA/J MGP_CBAJ_G0025945
protein coding gene Chr2:120706764-121048941 (-)
DBA/2J MGP_DBA2J_G0026083
protein coding gene Chr2:107788166-108080270 (-)
FVB/NJ MGP_FVBNJ_G0026046
protein coding gene Chr2:106705483-107005095 (-)
LP/J MGP_LPJ_G0026186
protein coding gene Chr2:113200589-113521121 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026070
protein coding gene Chr2:124892762-125280423 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026722
protein coding gene Chr2:111499445-111811091 (-)
PWK/PhJ MGP_PWKPhJ_G0025167
protein coding gene Chr2:107400957-107698389 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024967
protein coding gene Chr2:110740685-111075074 (-)
WSB/EiJ MGP_WSBEiJ_G0025499
protein coding gene Chr2:112245621-112565032 (-)



Homology
more
  • Human Ortholog
    ANO3, anoctamin 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ANO3, anoctamin 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C11orf25, DYT23, DYT24, GENX-3947, TMEM16C
  • Links
    NCBI Gene ID: 63982
    neXtProt AC: NX_Q9BYT9
    UniProt: Q9BYT9

  • Chr Location
    11p14.3-p14.2; chr11:26189123-26663289 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 57147
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: ANO3
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human ANO3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 228432 NCBI Gene Model | MGI Sequence Detail 295204 C57BL/6J ±  kb
transcript NM_001128103 RefSeq | MGI Sequence Detail 6026 C57BL/6  
polypeptide A2AHL1 UniProt | EBI | MGI Sequence Detail 981 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 3
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGI:2139060, MGI:3045304
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:221155 Quintens R, et al., Identification of novel radiation-induced p53-dependent transcripts extensively regulated during mouse brain development. Biol Open. 2015;4(3):331-44

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/13/2019
MGI 6.14
The Jackson Laboratory