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Ano3
Gene Detail
Symbol

Name
ID
Ano3
anoctamin 3
MGI:3613666
Synonyms
B230324K02Rik, Tmem16c
Feature Type
protein coding gene
Genetic Map
Chromosome 2
56.75 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:110655201-110950923 bp, - strand
From VEGA annotation of GRCm38

  295723 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:57147  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: ANO3
Gene Tree: Ano3

Human
homologs
ANO3, anoctamin 3
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 63982
neXtProt AC: NX_Q9BYT9

Human Synonyms: C11orf25, DYT23, DYT24, GENX-3947, TMEM16C

Human Chr (Location): 11p14.2; chr11:26188821-26668409 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human ANO3

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Ano3 interacts with 368 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (102)    Tissues (86)    Images (38)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 102
cDNA source data(3)
Other mouse links: GEO   Expression Atlas
Molecular
reagents
All nucleic(3) cDNA(3)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000015134 (Evidence)
Ensembl Gene Model ENSMUSG00000074968 (Evidence)
Entrez Gene 228432 (Evidence)
DFCI TC1697724, TC1653751, TC1605370
DoTS DT.94210816, DT.55178446, DT.91418252
Consensus CDS Project CCDS50657.1, CCDS50658.1
International Mouse Phenotyping Consortium Status Ano3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015134 VEGA Gene Model | MGI Sequence Detail 295723 C57BL/6J ±  kb
transcript OTTMUST00000035936 VEGA | MGI Sequence Detail 6705 Not Applicable 
polypeptide OTTMUSP00000016132 VEGA | MGI Sequence Detail 981 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(11) UniProt(2)
Polymorphisms
SNPs within 2kb(2200 from dbSNP Build 137)    SNPs within 2kb including multiple locations(2202)
Protein-related
information
ResourceIDDescription
InterPro IPR007632 Anoctamin/TMEM 16
Protein Ontology PR:000004058 anoctamin-3
References
(Earliest) J:138798 Rock JR, et al., Expression of TMEM16 paralogs during murine embryogenesis. Dev Dyn. 2008 Sep;237(9):2566-74
(Latest) J:198369 Suzuki J, et al., Calcium-dependent phospholipid scramblase activity of TMEM16 protein family members. J Biol Chem. 2013 May 10;288(19):13305-16
All references(26)
Other
accession IDs
MGI:2139060, MGI:3045304

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory