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Ehbp1l1 Gene Detail
Summary
  • Symbol
    Ehbp1l1
  • Name
    EH domain binding protein 1-like 1
  • Synonyms
    G430002G23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3612340
    NCBI Gene: 114601
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:5707376-5726317 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 4.34 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    106 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3612340
protein coding gene Chr19:5707369-5726461 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024724
protein coding gene Chr19:2691785-2712167 (-)
A/J MGP_AJ_G0024690
protein coding gene Chr19:2546509-2566360 (-)
AKR/J MGP_AKRJ_G0024663
protein coding gene Chr19:2612948-2635048 (-)
BALB/cJ MGP_BALBcJ_G0024690
protein coding gene Chr19:2540904-2561469 (-)
C3H/HeJ MGP_C3HHeJ_G0024458
protein coding gene Chr19:2631195-2650118 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025137
protein coding gene Chr19:2759429-2782596 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022567
protein coding gene Chr19:2455471-2475729 (-)
CAST/EiJ MGP_CASTEiJ_G0023930
protein coding gene Chr19:2650587-2669910 (-)
CBA/J MGP_CBAJ_G0024430
protein coding gene Chr19:2884897-2910444 (-)
DBA/2J MGP_DBA2J_G0024557
protein coding gene Chr19:2542420-2561608 (-)
FVB/NJ MGP_FVBNJ_G0024523
protein coding gene Chr19:2539951-2558770 (-)
LP/J MGP_LPJ_G0024643
protein coding gene Chr19:2667735-2687192 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024553
protein coding gene Chr19:2729479-2748371 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025185
protein coding gene Chr19:2633177-2652120 (-)
PWK/PhJ MGP_PWKPhJ_G0023676
protein coding gene Chr19:2565100-2585259 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023481
protein coding gene Chr19:2617486-2638171 (-)
WSB/EiJ MGP_WSBEiJ_G0023992
protein coding gene Chr19:2644243-2663196 (-)



Homology
more
  • Human Ortholog
    EHBP1L1, EH domain binding protein 1 like 1
  • Vertebrate Orthologs
    4
  • Human Ortholog
    EHBP1L1, EH domain binding protein 1 like 1
    Orthology source: HGNC
  • Links
    NCBI Gene ID: 254102
    neXtProt AC: NX_Q8N3D4
    UniProt: Q8N3D4

  • Chr Location
    11q13.1; chr11:65576034-65592650 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    36 phenotypes from 2 alleles in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous knockout leads to a reduction in the length and density of small intestinal microvilli, severe anemia, and neonatal lethality.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000024937 Ensembl Gene Model | MGI Sequence Detail 18942 C57BL/6J ±  kb
    transcript ENSMUST00000049295 Ensembl | MGI Sequence Detail 6404 Not Applicable  
    polypeptide ENSMUSP00000037656 Ensembl | MGI Sequence Detail 1718 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 72
      cDNA 71
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 3
      Gene Ontology 2
      Phenotypes 9
    • Earliest
      J:75685 Chauhan BK, et al., Identification of genes downstream of Pax6 in the mouse lens using cDNA microarrays. J Biol Chem. 2002 Mar 29;277(13):11539-48
    • Latest
      J:261440 Sobajima T, et al., The Rab11-binding protein RELCH/KIAA1468 controls intracellular cholesterol distribution. J Cell Biol. 2018 May 7;217(5):1777-1796

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    09/05/2019
    MGI 6.14
    The Jackson Laboratory