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Kcnmb3 Gene Detail
Summary
  • Symbol
    Kcnmb3
  • Name
    potassium large conductance calcium-activated channel, subfamily M, beta member 3
  • Synonyms
    Gm5707
  • Feature Type
    protein coding gene
  • IDs
    MGI:3612244
    NCBI Gene: 100502876
  • Gene Overview
    MyGene.info: KCNMB3
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr3:32471588-32492231 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 15.73 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    189 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3612244
protein coding gene Chr3:32467779-32502896 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027137
protein coding gene Chr3:30075620-30102399 (-)
A/J MGP_AJ_G0027097
protein coding gene Chr3:29652117-29673103 (-)
AKR/J MGP_AKRJ_G0027066
protein coding gene Chr3:30111565-30135208 (-)
BALB/cJ MGP_BALBcJ_G0027109
protein coding gene Chr3:29306675-29326321 (-)
C3H/HeJ MGP_C3HHeJ_G0026852
protein coding gene Chr3:30136485-30156718 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027555
protein coding gene Chr3:31576281-31599421 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024916
protein coding gene Chr3:27486190-27506695 (-)
CAST/EiJ MGP_CASTEiJ_G0026305
protein coding gene Chr3:29997919-30024198 (-)
CBA/J MGP_CBAJ_G0026829
protein coding gene Chr3:32412829-32438876 (-)
DBA/2J MGP_DBA2J_G0026963
protein coding gene Chr3:29124276-29145076 (-)
FVB/NJ MGP_FVBNJ_G0026931
protein coding gene Chr3:28585659-28606411 (-)
LP/J MGP_LPJ_G0027075
protein coding gene Chr3:30844676-30865762 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026951
protein coding gene Chr3:34934243-34954482 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027614
protein coding gene Chr3:29908159-29926133 (-)
PWK/PhJ MGP_PWKPhJ_G0026038
protein coding gene Chr3:28668135-28688588 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025850
protein coding gene Chr3:29310822-29332677 (-)
WSB/EiJ MGP_WSBEiJ_G0026379
protein coding gene Chr3:29915585-29937659 (-)



Homology
more
  • Human Ortholog
    KCNMB3, potassium calcium-activated channel subfamily M regulatory beta subunit 3
  • Vertebrate Orthologs
    6
  • Human Ortholog
    KCNMB3, potassium calcium-activated channel subfamily M regulatory beta subunit 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BKBETA3, HBETA3, KCNMB2, KCNMBL, K(VCA)BETA-3, SLOBETA3, SLO-BETA-3
  • Links
    NCBI Gene ID: 27094
    neXtProt AC: NX_Q9NPA1
    UniProt: Q9NPA1

  • Chr Location
    3q26.32; chr3:179239749-179267050 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000091091 Ensembl Gene Model | MGI Sequence Detail 20644 C57BL/6J ±  kb
transcript ENSMUST00000164954 Ensembl | MGI Sequence Detail 1715 Not Applicable  
polypeptide ENSMUSP00000130177 Ensembl | MGI Sequence Detail 239 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR003930 Potassium channel, calcium-activated, BK, beta subunit
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1
Other
Accession IDs
less
MGI:3647479
References
more
  • Summaries
    All 18
    Diseases 1
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:239914 Hayashi Y, et al., BK channels in microglia are required for morphine-induced hyperalgesia. Nat Commun. 2016 May 31;7:11697

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory