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Ccdc8 Gene Detail
Summary
  • Symbol
    Ccdc8
  • Name
    coiled-coil domain containing 8
  • Synonyms
    ENSMUSG00000041117
  • Feature Type
    protein coding gene
  • IDs
    MGI:3612184
    NCBI Gene: 434130
  • Gene Overview
    MyGene.info: CCDC8
Location & Maps
more
  • Sequence Map
    Chr7:16992708-16997516 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4809 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 9.15 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CCDC8, coiled-coil domain containing 8
  • Vertebrate Orthologs
    7
  • Human Ortholog
    CCDC8, coiled-coil domain containing 8
    Orthology source: HomoloGene
  • Synonyms
    3M3, p90, PPP1R20
  • Links
    NCBI Gene ID: 83987
    neXtProt AC: NX_Q9H0W5

  • Chr Location
    19q13.32; chr19:46410329-46413662 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human CCDC8 associations

Human Disease Mouse Models
       Three M Syndrome 3; 3M3   OMIM: 614205
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037103 VEGA Gene Model | MGI Sequence Detail 4809 C57BL/6J ±  kb
transcript OTTMUST00000095517 VEGA | MGI Sequence Detail 4809 Not Applicable  
polypeptide OTTMUSP00000063110 VEGA | MGI Sequence Detail 685 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    75 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000029348 coiled-coil domain-containing protein 8
  • InterPro Domains
    IPR026526 Coiled-coil domain-containing protein 8
    IPR026523 Paraneoplastic antigen Ma
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 1
Other
Accession IDs
less
MGI:3641939
References
more
  • Summaries
    All 18
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory