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Bin2 Gene Detail
Summary
  • Symbol
    Bin2
  • Name
    bridging integrator 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:3611448
    NCBI Gene: 668218
Location & Maps
more
  • Genetic Map
    Chromosome 15, 56.37 cM
  • Mapping Data
    1 experiment
Homology
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  • Human Ortholog
    BIN2, bridging integrator 2
  • Vertebrate Orthologs
    7
  • Human Ortholog
    BIN2, bridging integrator 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BRAP-1
  • Links
    NCBI Gene ID: 51411
    neXtProt AC: NX_Q9UBW5

  • Chr Location
    12q13; chr12:51281038-51324680 (-)  GRCh38.p2

Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    19 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Genomic Mutations
    3 involving Bin2
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Other Mouse Links
  • Other Vertebrate Links
    Xenbase bin2
    ZFIN bin2b
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000043210 VEGA Gene Model | MGI Sequence Detail 28477 C57BL/6J ±  kb
transcript OTTMUST00000113348 VEGA | MGI Sequence Detail 2036 Not Applicable  
polypeptide OTTMUSP00000063401 VEGA | MGI Sequence Detail 505 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    192 from dbSNP Build 142
Protein
Information
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Molecular
Reagents
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  • All nucleic 9
    cDNA 9
References
more
  • Summaries
    All 13
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 1
    Phenotypes 19
  • Earliest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support.
last database update
09/27/2016
MGI 6.05
The Jackson Laboratory