About   Help   FAQ
Tmem132b Gene Detail
Summary
  • Symbol
    Tmem132b
  • Name
    transmembrane protein 132B
  • Feature Type
    protein coding gene
  • IDs
    MGI:3609245
    NCBI Gene: 208151
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:125532418-125792583 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 64.27 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1935 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3609245
protein coding gene Chr5:125531774-125792583 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030114
protein coding gene Chr5:129392007-129654287 (+)
A/J MGP_AJ_G0030081
protein coding gene Chr5:123966060-124222249 (+)
AKR/J MGP_AKRJ_G0030015
protein coding gene Chr5:127994384-128258841 (+)
BALB/cJ MGP_BALBcJ_G0030091
protein coding gene Chr5:125300385-125561835 (+)
C3H/HeJ MGP_C3HHeJ_G0029808
protein coding gene Chr5:128597234-128860101 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030544
protein coding gene Chr5:134396582-134671003 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027769
protein coding gene Chr5:118498817-118753813 (+)
CAST/EiJ MGP_CASTEiJ_G0029217
protein coding gene Chr5:127740101-128004764 (+)
CBA/J MGP_CBAJ_G0029778
protein coding gene Chr5:139669972-139952277 (+)
DBA/2J MGP_DBA2J_G0029928
protein coding gene Chr5:123982101-124239222 (+)
FVB/NJ MGP_FVBNJ_G0029884
protein coding gene Chr5:123062943-123324973 (+)
LP/J MGP_LPJ_G0030017
protein coding gene Chr5:129906717-130179711 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029915
protein coding gene Chr5:143173034-143436350 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030585
protein coding gene Chr5:127605599-127873510 (+)
PWK/PhJ MGP_PWKPhJ_G0028931
protein coding gene Chr5:122821769-123084227 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028768
protein coding gene Chr5:125246237-125512857 (+)
WSB/EiJ MGP_WSBEiJ_G0029291
protein coding gene Chr5:128308148-128570983 (+)



Homology
more
  • Human Ortholog
    TMEM132B, transmembrane protein 132B
  • Vertebrate Orthologs
    8
  • Human Ortholog
    TMEM132B, transmembrane protein 132B
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 114795
    neXtProt AC: NX_Q14DG7
    UniProt: Q14DG7

  • Chr Location
    12q24.31-q24.32; chr12:125186750-125662377 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 208151 NCBI Gene Model | MGI Sequence Detail 260166 C57BL/6J ±  kb
    transcript NM_001190352 RefSeq | MGI Sequence Detail 7964 C57BL/6  
    polypeptide NP_001177281 RefSeq | MGI Sequence Detail 1078 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • InterPro Domains
      IPR026307 Transmembrane protein 132
      IPR031437 Transmembrane protein family 132, middle domain
      IPR031436 Transmembrane protein TMEM132, C-terminal
      IPR031435 Transmembrane protein TMEM132, N-terminal
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13

      Microarray probesets 3
    References
    more
    • Summaries
      All 20
      Phenotypes 9
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer & Copyright Notice
    Send questions and comments to User Support.
    last database update
    10/13/2020
    MGI 6.16
    The Jackson Laboratory