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Lonrf1 Gene Detail
Summary
  • Symbol
    Lonrf1
  • Name
    LON peptidase N-terminal domain and ring finger 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:3609241
    NCBI Gene: 244421
Location & Maps
more
  • Sequence Map
    Chr8:36216064-36249516 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      33453 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 23.05 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    LONRF1, LON peptidase N-terminal domain and ring finger 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LONRF1, LON peptidase N-terminal domain and ring finger 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    RNF191
  • Links
    NCBI Gene ID: 91694
    neXtProt AC: NX_Q17RB8

  • Chr Location
    8p23.1; chr8:12721897-12755485 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 34980
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: LONRF1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotype references
  • All Mutations and Alleles
    2
  • Gene trapped
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000061048 VEGA Gene Model | MGI Sequence Detail 33453 C57BL/6J ±  kb
transcript OTTMUST00000149160 VEGA | MGI Sequence Detail 3930 Not Applicable  
polypeptide OTTMUSP00000077433 VEGA | MGI Sequence Detail 837 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    544 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000030891 LON peptidase N-terminal domain and RING finger protein 1
  • InterPro Domains
    IPR003111 ATP-dependent protease La (LON), substrate-binding domain
    IPR015947 PUA-like domain
    IPR027370 RING-type zinc-finger, LisH dimerisation motif
    IPR011990 Tetratricopeptide-like helical domain
    IPR019734 Tetratricopeptide repeat
    IPR013026 Tetratricopeptide repeat-containing domain
    IPR013083 Zinc finger, RING/FYVE/PHD-type
    IPR001841 Zinc finger, RING-type
    IPR017907 Zinc finger, RING-type, conserved site
Molecular
Reagents
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  • All nucleic 2
    cDNA 2

    Microarray probesets 3
References
more
  • Summaries
    All 17
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:91812 Stryke D, et al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Nucleic Acids Res. 2003 Jan 1;31(1):278-81
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory