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Selenov Gene Detail
Summary
  • Symbol
    Selenov
  • Name
    selenoprotein V
  • Synonyms
    BC089491
  • Feature Type
    protein coding gene
  • IDs
    MGI:3608324
    NCBI Gene: 280621
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:27984077-27990611 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 16.67 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    272 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3608324
 protein coding gene Chr7:27984077-27990611 (-)
129S1/SvImJ ENSMUSG00200040855
 protein coding gene Chr7:17769866-17776417 (-)
A/J ENSMUSG00195049065
 protein coding gene Chr7:20443077-20449626 (-)
AKR/J ENSMUSG00220049912
 protein coding gene Chr7:24036311-24042846 (+)
BALB/cJ ENSMUSG00180050350
 protein coding gene Chr7:18502620-18509167 (-)
C3H/HeJ ENSMUSG00175041719
 protein coding gene Chr7:19538281-19544810 (-)
C57BL/6NJ ENSMUSG00215052734
 protein coding gene Chr7:17673883-17680417 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029438
 protein coding gene Chr7:27482184-27489153 (-)
CAST/EiJ ENSTCUG00005048551
 protein coding gene Chr7:19460065-19466985 (-)
CBA/J ENSMUSG00210052530
 protein coding gene Chr7:18722876-18729405 (-)
DBA/2J ENSMUSG00185045180
 protein coding gene Chr7:21835552-21842085 (-)
FVB/NJ ENSMUSG00205047602
 protein coding gene Chr7:18508154-18514695 (-)
JF1/MsJ ENSUMUG00000052470
 protein coding gene Chr7:26235997-26242915 (-)
LP/J ENSMUSG00230053325
 protein coding gene Chr7:27006093-27012628 (-)
NOD/ShiLtJ ENSMUSG00190043231
 protein coding gene Chr7:18169847-18176382 (-)
NZO/HlLtJ ENSMUSG00225023670
 protein coding gene Chr7:25849217-25855751 (-)
PWK/PhJ ENSLUMG00010044564
 protein coding gene Chr7:18199949-18206839 (-)
SPRET/EiJ ENSMSPG00010037405
 protein coding gene Chr7:17564340-17567908 (-)
WSB/EiJ ENSIUOG00005053295
 protein coding gene Chr7:12430239-12436784 (-)



Homology
more
  • Human Ortholog
    SELENOV, selenoprotein V
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SELENOV, selenoprotein V
  • Synonyms
    SELV
  • Links
    NCBI Gene ID: 348303
    UniProt: P59797

  • Chr Location
    19q13.2; chr19:39515113-39520686 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    39 phenotypes from 2 alleles in 2 genetic backgrounds
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele show reduced energy expenditure and increased body weight due to extra fat accumulation and exhibit increased endoplasmic reticulum stress, oxidative injury and cellular respiration dysfunction in response to pro-oxidant treatment.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 280621 NCBI Gene Model | MGI Sequence Detail 6535 C57BL/6J ±  kb
    transcript NM_175033 RefSeq | MGI Sequence Detail 1277 C57BL/6  
    polypeptide NP_778198 RefSeq | MGI Sequence Detail 328 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • InterPro Domains
      IPR011893 Selenoprotein, Rdx-type
      IPR051441 Selenoprotein W and related
      IPR036249 Thioredoxin-like superfamily
    • GlyGen
      Q5FWB9 1 site
    Molecular
    Reagents
    less
    • All nucleic 4
      cDNA 4

      Microarray probesets 1
    References
    more
    • Summaries
      All 18
      Phenotypes 6
    • Earliest
      J:234235 Miyata H, et al., Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7704-10
    • Latest
      J:311586 Chen LL, et al., Loss of Selenov predisposes mice to extra fat accumulation and attenuated energy expenditure. Redox Biol. 2021 Sep;45:102048
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory