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Rft1 Gene Detail
Summary
  • Symbol
    Rft1
  • Name
    RFT1 homolog
  • Feature Type
    protein coding gene
  • IDs
    MGI:3607791
    NCBI Gene: 328370
  • Gene Overview
    MyGene.info: RFT1
Location & Maps
more
  • Sequence Map
    Chr14:30654360-30691317 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      36958 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 18.90 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    RFT1, RFT1 homolog
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RFT1, RFT1 homolog
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CDG1N
  • Links
    NCBI Gene ID: 91869
    neXtProt AC: NX_Q96AA3

  • Chr Location
    3p21.1; chr3:53071152-53130459 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 5343
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: RFT1
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human RFT1 associations

Human Disease Mouse Models
       Congenital Disorder of Glycosylation, Type In; CDG1N   OMIM: 612015
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    10
  • Gene trapped
    7
  • Targeted
    3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025088 VEGA Gene Model | MGI Sequence Detail 36958 C57BL/6J ±  kb
transcript OTTMUST00000061730 VEGA | MGI Sequence Detail 2387 Not Applicable  
polypeptide OTTMUSP00000030345 VEGA | MGI Sequence Detail 541 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    181 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 1
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory