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Bex4 Gene Detail
Summary
  • Symbol
    Bex4
  • Name
    brain expressed X-linked 4
  • Feature Type
    protein coding gene
  • IDs
    MGI:3606746
    NCBI Gene: 406217
  • Gene Overview
    MyGene.info: BEX4
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:136139045-136140439 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 57.40 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    25 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3606746
protein coding gene ChrX:136138996-136140443 (.)
129S1/SvImJ MGP_129S1SvImJ_G0016573
protein coding gene Chr1:154909351-154911355 (-)
A/J MGP_AJ_G0018310
protein coding gene Chr11:55423229-55430703 (-)
AKR/J MGP_AKRJ_G0018279
protein coding gene Chr11:57244066-57244510 (-)
BALB/cJ MGP_BALBcJ_G0018281
protein coding gene Chr11:55765027-55765641 (-)
C3H/HeJ MGP_C3HHeJ_G0035773
protein coding gene ChrX:133490353-133490962 (+)
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0017657
protein coding gene Chr11:57259262-57262066 (-)
CBA/J MGP_CBAJ_G0018067
protein coding gene Chr11:62098033-62098607 (-)
DBA/2J MGP_DBA2J_G0018176
protein coding gene Chr11:55070139-55070753 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0018251
protein coding gene Chr11:58131518-58138302 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035874
protein coding gene ChrX:148954431-148955878 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018775
protein coding gene Chr11:57269628-57274532 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0034584
protein coding gene ChrX:115060882-115062391 (+)
WSB/EiJ MGP_WSBEiJ_G0035195
protein coding gene ChrX:131189786-131191240 (+)



Homology
more
  • Human Ortholog
    BEX4, brain expressed X-linked 4
  • Vertebrate Orthologs
    9
  • Human Ortholog
    BEX4, brain expressed X-linked 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BEXL1
  • Links
    NCBI Gene ID: 56271
    neXtProt AC: NX_Q9NWD9
    UniProt: Q9NWD9

  • Chr Location
    Xq22.1; chrX:103215092-103217200 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 406217 NCBI Gene Model | MGI Sequence Detail 1395 C57BL/6J ±  kb
transcript NM_212457 RefSeq | MGI Sequence Detail 859 C57BL/6  
polypeptide Q9CWT2 UniProt | EBI | MGI Sequence Detail 118 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 34
    cDNA 34

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:243608 Yu W, et al., BEX4 upregulation alters Sertoli cell growth properties and protein expression profiles: An explanation for cadmium-induced testicular Sertoli cell injury. J Biochem Mol Toxicol. 2017 Jul;31(7)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory