Btn2a2
Gene Detail

Symbol Name ID

Btn2a2 butyrophilin, subfamily 2, member A2 MGI:3606486

Feature Type

protein coding gene

Genetic Map

Chromosome 13

9.74 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr13:23477676-23488857 bp, - strand From VEGA annotation of GRCm38   11182 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:56012  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 2 zebrafish

Protein SuperFamily: butyrophilin
Gene Tree: Btn2a2

Human homologs

Human Homolog		BTN2A2, butyrophilin, subfamily 2, member A2
NCBI Gene ID		10385
neXtProt AC		NX_Q8WVV5
Human Synonyms		BT2.2, BTF2
Human Chr (Location)		6p22.1; chr6:26383324-26395102 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(7) : Targeted(3) Gene trapped(4)

Gene Ontology (GO) classifications

All GO classifications: (6 annotations)

Process	negative regulation of activated T cell proliferation, negative regulation of cellular metabolic process, ...
Component	integral to membrane, membrane
Function	molecular_function

External Resources: FuncBase

Expression

cDNA source data(2)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(3) Genomic(1) cDNA(2)
Microarray probesets(1)

Other database links

VEGA Gene Model	OTTMUSG00000000552 (Evidence)
Ensembl Gene Model	ENSMUSG00000053216 (Evidence)
Entrez Gene	238555 (Evidence)
UniGene	129668
DFCI	TC1589870, TC1598615
DoTS	DT.101710180, DT.94164259
NIA Mouse Gene Index	U165029
Consensus CDS Project	CCDS36619.1
International Mouse Knockout Project Status	Btn2a2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000000552	VEGA Gene Model | MGI Sequence Detail	11182	C57BL/6J
transcript	OTTMUST00000001139	VEGA | MGI Sequence Detail	2370	Not Applicable
polypeptide	OTTMUSP00000000520	VEGA | MGI Sequence Detail	514	Not Applicable

All sequences(30) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(38 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001870	B30.2/SPRY domain
InterPro	IPR003879	Butyrophylin-like
InterPro	IPR013162	CD80-like, immunoglobulin C2-set
InterPro	IPR008985	Concanavalin A-like lectin/glucanases superfamily
InterPro	IPR007110	Immunoglobulin-like domain
InterPro	IPR013783	Immunoglobulin-like fold
InterPro	IPR003599	Immunoglobulin subtype
InterPro	IPR013106	Immunoglobulin V-set
InterPro	IPR003877	SPla/RYanodine receptor SPRY
InterPro	IPR018355	SPla/RYanodine receptor subgroup
InterPro	IPR006574	SPRY-associated
Protein Ontology	PR:000032222	butyrophilin subfamily 2 member A2

References

(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(26)