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Btn2a2 Gene Detail
Summary
  • Symbol
    Btn2a2
  • Name
    butyrophilin, subfamily 2, member A2
  • Feature Type
    protein coding gene
  • IDs
    MGI:3606486
    NCBI Gene: 238555
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr13:23477676-23488857 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 9.74 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    84 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3606486
protein coding gene Chr13:23477049-23488858 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020343
protein coding gene Chr13:20883983-20896297 (-)
A/J MGP_AJ_G0020300
protein coding gene Chr13:20514568-20525933 (-)
AKR/J MGP_AKRJ_G0020272
protein coding gene Chr13:20754679-20765758 (-)
BALB/cJ MGP_BALBcJ_G0020286
protein coding gene Chr13:20505313-20516560 (-)
C3H/HeJ MGP_C3HHeJ_G0020095
protein coding gene Chr13:20837039-20848313 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020731
protein coding gene Chr13:21625822-21659583 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018315
protein coding gene Chr13:19316692-19329099 (-)
CAST/EiJ MGP_CASTEiJ_G0019617
protein coding gene Chr13:20523849-20535290 (-)
CBA/J MGP_CBAJ_G0020046
protein coding gene Chr13:22484685-22500602 (-)
DBA/2J MGP_DBA2J_G0020172
protein coding gene Chr13:20084028-20095309 (-)
FVB/NJ MGP_FVBNJ_G0020160
protein coding gene Chr13:19703333-19714524 (-)
LP/J MGP_LPJ_G0020245
protein coding gene Chr13:21210103-21222833 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020190
protein coding gene Chr13:22804025-22814966 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020761
protein coding gene Chr13:20607413-20618594 (-)
PWK/PhJ MGP_PWKPhJ_G0019372
protein coding gene Chr13:20072442-20083457 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019183
protein coding gene Chr13:19409226-19422836 (-)
WSB/EiJ MGP_WSBEiJ_G0019673
protein coding gene Chr13:20736429-20747652 (-)



Homology
more
  • Human Ortholog
    BTN2A2, butyrophilin subfamily 2 member A2
  • Vertebrate Orthologs
    7
  • Human Ortholog
    BTN2A2, butyrophilin subfamily 2 member A2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BT2.2, BTF2, BTN2.2
  • Links
    NCBI Gene ID: 10385
    neXtProt AC: NX_Q8WVV5
    UniProt: Q8WVV5

  • Chr Location
    6p22.2; chr6:26382891-26394874 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053216 Ensembl Gene Model | MGI Sequence Detail 11182 C57BL/6J ±  kb
transcript ENSMUST00000110433 Ensembl | MGI Sequence Detail 2370 Not Applicable  
polypeptide ENSMUSP00000106063 Ensembl | MGI Sequence Detail 514 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    Genomic 2
    cDNA 2

    Microarray probesets 1
References
more
  • Summaries
    All 32
    Gene Ontology 5
    Phenotypes 15
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:232636 Sarter K, et al., Btn2a2, a T cell immunomodulatory molecule coregulated with MHC class II genes. J Exp Med. 2016 Feb 8;213(2):177-87

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory