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Prss45
Gene Detail
 Symbol
Name
ID
Prss45
protease, serine 45
MGI:3605764
Feature Type protein coding gene
Genetic Map
Chromosome 9
60.79 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr9:110834588-110841313 bp, + strand
From VEGA annotation of GRCm38

  6726 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:51905  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: trypsin
Gene Tree: Prss45

Human
homologs
Human Homolog PRSS45, protease, serine, 45
NCBI Gene ID 377047
neXtProt AC  NX_Q7RTY3
Human Synonyms  TESSP5
Human Chr (Location)  3p21.31; chr3:46742091-46744755 (-)  GRCh38
Alleles
and
phenotypes
All alleles(6) : Gene trapped(4) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process proteolysis
Component extracellular region
Function catalytic activity, serine-type endopeptidase activity
External Resources: FuncBase
Expression
cDNA source data(6)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(6) cDNA(6)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000034119 (Evidence)
Ensembl Gene ModelENSMUSG00000047257 (Evidence)
Entrez Gene260408 (Evidence)
UniGene79114
DFCITC1587720
DoTSDT.110640855, DT.91418823
NIA Mouse Gene IndexU056498
Consensus CDS ProjectCCDS23575.1
International Mouse Knockout Project StatusPrss45
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034119 VEGA Gene Model | MGI Sequence Detail 6726 C57BL/6J ±  kb
transcript OTTMUST00000086320 VEGA | MGI Sequence Detail 1235 Not Applicable 
polypeptide OTTMUSP00000046725 VEGA | MGI Sequence Detail 317 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(107 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000031024 serine protease 45
References (Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory