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Acaa1b Gene Detail
Summary
  • Symbol
    Acaa1b
  • Name
    acetyl-Coenzyme A acyltransferase 1B
  • Synonyms
    thiolase B
  • Feature Type
    protein coding gene
  • IDs
    MGI:3605455
    NCBI Gene: 235674
  • Gene Overview
    MyGene.info: ACAA1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:119148043-119157093 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 71.33 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    76 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3605455
protein coding gene Chr9:119148023-119157093 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035412
protein coding gene Chr9:121861695-121878481 (-)
A/J MGP_AJ_G0035392
protein coding gene Chr9:117364552-117374031 (-)
AKR/J MGP_AKRJ_G0035325
protein coding gene Chr9:120401300-120414709 (-)
BALB/cJ MGP_BALBcJ_G0035388
protein coding gene Chr9:117233741-117243697 (-)
C3H/HeJ MGP_C3HHeJ_G0035096
protein coding gene Chr9:120871597-120884855 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035911
protein coding gene Chr9:125209583-125227888 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032794
protein coding gene Chr9:114556370-114565737 (-)
CAST/EiJ MGP_CASTEiJ_G0034400
protein coding gene Chr9:120840794-120848950 (-)
CBA/J MGP_CBAJ_G0035063
protein coding gene Chr9:129918412-129927257 (-)
DBA/2J MGP_DBA2J_G0035222
protein coding gene Chr9:116802082-116812619 (-)
FVB/NJ MGP_FVBNJ_G0035169
protein coding gene Chr9:115646926-115656105 (-)
LP/J MGP_LPJ_G0035301
protein coding gene Chr9:122214284-122227171 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035210
protein coding gene Chr9:130902034-130910324 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035930
protein coding gene Chr9:120791571-120802746 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0033941
protein coding gene Chr9:120904787-120920313 (-)
WSB/EiJ MGP_WSBEiJ_G0034521
protein coding gene Chr9:120680440-120687835 (-)



Homology
more
  • Human Ortholog
    ACAA1, acetyl-CoA acyltransferase 1
  • Vertebrate Orthologs
    1
  • Human Ortholog
    ACAA1, acetyl-CoA acyltransferase 1
    Orthology source: HGNC
  • Synonyms
    ACAA, PTHIO, THIO
  • Links
    NCBI Gene ID: 30
    neXtProt AC: NX_P09110
    UniProt: P09110

  • Chr Location
    3p22.2; chr3:38122710-38137242 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Mice homozygous for a disruption in this gene appear normal.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 235674 NCBI Gene Model | MGI Sequence Detail 9051 C57BL/6J ±  kb
transcript NM_146230 RefSeq | MGI Sequence Detail 1669 C57BL/6  
polypeptide Q8VCH0 UniProt | EBI | MGI Sequence Detail 424 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 132
    cDNA 131
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 35
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 12
  • Earliest
    J:12215 Chubb C, Oligotriche and quaking gene mutations. Phenotypic effects on mouse spermatogenesis and testicular steroidogenesis. J Androl. 1992 Jul-Aug;13(4):312-7
  • Latest
    J:187815 Runkel F, et al., Alopecia in a viable phospholipase C delta 1 and phospholipase C delta 3 double mutant. PLoS One. 2012;7(6):e39203

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory