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Acaa1b Gene Detail
Summary
  • Symbol
    Acaa1b
  • Name
    acetyl-Coenzyme A acyltransferase 1B
  • Synonyms
    thiolase B
  • Feature Type
    protein coding gene
  • IDs
    MGI:3605455
    NCBI Gene: 235674
Location & Maps
more
  • Sequence Map
    Chr9:119148023-119157093 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      9071 bp   ±  kb flank

  • Genome Browsers
Homology
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Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
  • All Mutations and Alleles
    2
  • Spontaneous
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Acaa1b
  • Incidental Mutations
Mice homozygous for a disruption in this gene appear normal.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033525 VEGA Gene Model | MGI Sequence Detail 9071 C57BL/6J ±  kb
transcript OTTMUST00000084360 VEGA | MGI Sequence Detail 1689 Not Applicable  
polypeptide OTTMUSP00000045451 VEGA | MGI Sequence Detail 424 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    76 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
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  • All nucleic 132
    cDNA 131
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 12
  • Earliest
    J:105494 Chevillard G, et al., Targeted disruption of the peroxisomal thiolase B gene in mouse: a new model to study disorders related to peroxisomal lipid metabolism. Biochimie. 2004 Nov;86(11):849-56
  • Latest
    J:171615 Georgas KM, et al., Expression of metanephric nephron-patterning genes in differentiating mesonephric tubules. Dev Dyn. 2011 Jun;240(6):1600-12

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory