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Slc28a1
Gene Detail
 Symbol
Name
ID
Slc28a1
solute carrier family 28 (sodium-coupled nucleoside transporter), member 1
MGI:3605073
Synonyms Cnt1
Feature Type protein coding gene
Genetic Map
Chromosome 7
45.71 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:81114799-81170416 bp, + strand
From VEGA annotation of GRCm38

  55618 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37902  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Slc28a1

Human
homologs
Human Homolog SLC28A1, solute carrier family 28 (concentrative nucleoside transporter), member 1
NCBI Gene ID 9154
neXtProt AC  NX_O00337
Human Synonyms  CNT1, HCNT1
Human Chr (Location)  15q25.3; chr15:84884604-84945796 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(34) : Gene trapped(32) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Slc28a1 interacts with 125 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process nucleoside transmembrane transport, purine nucleobase transport, ...
Component apical plasma membrane, membrane
Function pyrimidine- and adenine-specific:sodium symporter activity, pyrimidine nucleobase transmembrane transporter activity
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (99)    Tissues (95)    Images (6)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 99
cDNA source data(6)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(6) cDNA(6)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000031345 (Evidence)
Ensembl Gene ModelENSMUSG00000025726 (Evidence)
Entrez Gene434203 (Evidence)
UniGene389909
DFCITC1589675
DoTSDT.101295048
NIA Mouse Gene IndexU008294
Consensus CDS ProjectCCDS21402.1
International Mouse Knockout Project StatusSlc28a1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031345 VEGA Gene Model | MGI Sequence Detail 55618 C57BL/6J ±  kb
transcript OTTMUST00000077656 VEGA | MGI Sequence Detail 2846 Not Applicable 
polypeptide OTTMUSP00000041121 VEGA | MGI Sequence Detail 648 Not Applicable 

For the selected sequences
All sequences(28) RefSeq(11) UniProt(2)
Polymorphisms SNPs within 2kb(471 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008276 Concentrative nucleoside transporter
InterPro IPR018270 Concentrative nucleoside transporter, metazoan/bacterial
InterPro IPR002668 Na dependent nucleoside transporter
InterPro IPR011657 Na dependent nucleoside transporter, C-terminal
InterPro IPR011642 Nucleoside recognition Gate
Protein Ontology PR:000015051 sodium/nucleoside cotransporter 1
References (Earliest) J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory