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Il20ra
Gene Detail
 Symbol
Name
ID
Il20ra
interleukin 20 receptor, alpha
MGI:3605069
Feature Type protein coding gene
Genetic Map
Chromosome 10
8.76 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr10:19712587-19760053 bp, + strand
From NCBI annotation of GRCm38

  47467 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8685  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Il20ra

Human
homologs
Human Homolog IL20RA, interleukin 20 receptor, alpha
NCBI Gene ID 53832
neXtProt AC  NX_Q9UHF4
Human Synonyms  CRF2-8, IL-20R1, IL-20RA, IL-20R-alpha
Human Chr (Location)  6q23.3; chr6:136999971-137045180 (-)  GRCh38
Alleles
and
phenotypes
All alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit increased bone mineral density, impaired osteoclast differentiation, and resistance to ovariectomized-inducced bone loss.
 
Phenotype Images(1)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process cytokine-mediated signaling pathway, positive regulation of intrinsic apoptotic signaling pathway, ...
Component integral component of membrane, membrane
Function interleukin-20 binding
External Resources: FuncBase
Expression
cDNA source data(3)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(3) cDNA(3)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000020007 (Evidence)
Entrez Gene237313 (Evidence)
UniGene234667
DFCITC1588899
DoTSDT.91332037
Consensus CDS ProjectCCDS23718.1
International Mouse Knockout Project StatusIl20ra
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 237313 NCBI Gene Model | MGI Sequence Detail 47467 C57BL/6J ±  kb
transcript NM_172786 RefSeq | MGI Sequence Detail 2088 C57BL/6 
polypeptide Q6PHB0 UniProt | EBI | MGI Sequence Detail 546 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(10) UniProt(2)
Polymorphisms SNPs within 2kb(218 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003961 Fibronectin, type III
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR015373 Interferon alpha/beta receptor, beta chain
InterPro IPR015713 Interleukin-20 receptor, alpha subunit
Protein Ontology PR:000008996 interleukin-20 receptor subunit alpha
Graphical View of Protein Domain Structure
References (Earliest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
(Latest) J:197173 Hsu YH, et al., Interleukin-19 mediates tissue damage in murine ischemic acute kidney injury. PLoS One. 2013;8(2):e56028
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory