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Zmynd15
Gene Detail
Symbol

Name
ID
Zmynd15
zinc finger, MYND-type containing 15
MGI:3603821
Feature Type
protein coding gene
Genetic Map
Chromosome 11
42.99 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:70459433-70466202 bp, + strand
From VEGA annotation of GRCm38

  6770 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12995  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: ZMYND15
Gene Tree: Zmynd15

Human
homologs
ZMYND15, zinc finger, MYND-type containing 15
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 84225
neXtProt AC: NX_Q9H091

Human Synonyms: SPGF14

Human Chr (Location): 17p13.2; chr17:4740015-4746119 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human ZMYND15

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Genomic Mutations involving Zmynd15 (2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a knock-out allele of Cxcl16 and Zmynd15 exhibit abnormal spermiogenesis and reduced male fertility.
 
Phenotype Images(4)
Interactions
Zmynd15 interacts with 20 markers (Mir1a-1, Mir1a-2, Mir7-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (43)    Tissues (29)    Images (13)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 43
cDNA source data(15)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(15) cDNA(15)
Microarray probesets(1)
Other database
links
VEGA Gene Model OTTMUSG00000006043 (Evidence)
Ensembl Gene Model ENSMUSG00000040829 (Evidence)
Entrez Gene 574428 (Evidence)
UniGene 472771
DFCI TC1585606, TC1592202
NIA Mouse Gene Index U012851
Consensus CDS Project CCDS24949.1
International Mouse Phenotyping Consortium Status Zmynd15
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006043 VEGA Gene Model | MGI Sequence Detail 6770 C57BL/6J ±  kb
transcript OTTMUST00000013605 VEGA | MGI Sequence Detail 2804 Not Applicable 
polypeptide OTTMUSP00000006310 VEGA | MGI Sequence Detail 736 Not Applicable 

For the selected sequences
All sequences(80) RefSeq(42) UniProt(5)
Polymorphisms
SNPs within 2kb(36 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002893 Zinc finger, MYND-type
Protein Ontology PR:000030687 zinc finger MYND domain-containing protein 15
References
(Earliest) J:123851 Aslanian AM, et al., Targeted disruption of the scavenger receptor and chemokine CXCL16 accelerates atherosclerosis. Circulation. 2006 Aug 8;114(6):583-90
(Latest) J:166802 Yan W, et al., Zmynd15 encodes a histone deacetylase-dependent transcriptional repressor essential for spermiogenesis and male fertility. J Biol Chem. 2010 Oct 8;285(41):31418-26
All references(20)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory