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Rufy4 Gene Detail
Summary
  • Symbol
    Rufy4
  • Name
    RUN and FYVE domain containing 4
  • Synonyms
    F930048N03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3588214
    NCBI Gene: 435626
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:74125541-74148223 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 38.38 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    253 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3588214
protein coding gene Chr1:74124618-74148230 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016140
protein coding gene Chr1:74707521-74732058 (+)
A/J MGP_AJ_G0016123
protein coding gene Chr1:72091824-72114248 (+)
AKR/J MGP_AKRJ_G0016080
protein coding gene Chr1:74096607-74120380 (+)
BALB/cJ MGP_BALBcJ_G0016078
protein coding gene Chr1:72163015-72183013 (+)
C3H/HeJ MGP_C3HHeJ_G0015909
protein coding gene Chr1:74421213-74447055 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016531
protein coding gene Chr1:77612995-77638551 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014252
protein coding gene Chr1:67671005-67693159 (+)
CAST/EiJ MGP_CASTEiJ_G0015493
protein coding gene Chr1:73730380-73756783 (+)
CBA/J MGP_CBAJ_G0015882
protein coding gene Chr1:80119980-80149904 (+)
DBA/2J MGP_DBA2J_G0015983
protein coding gene Chr1:71423084-71447695 (+)
FVB/NJ MGP_FVBNJ_G0015986
protein coding gene Chr1:70602408-70623300 (+)
LP/J MGP_LPJ_G0016055
protein coding gene Chr1:75800954-75825243 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016006
protein coding gene Chr1:83556773-83582169 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016578
protein coding gene Chr1:74145400-74169355 (+)
PWK/PhJ MGP_PWKPhJ_G0015280
protein coding gene Chr1:70864835-70889424 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015058
protein coding gene Chr1:73514534-73537484 (+)
WSB/EiJ MGP_WSBEiJ_G0015555
protein coding gene Chr1:73951085-73975279 (+)



Homology
more
  • Human Ortholog
    RUFY4, RUN and FYVE domain containing 4
  • Vertebrate Orthologs
    8
  • Human Ortholog
    RUFY4, RUN and FYVE domain containing 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ZFYVE31
  • Links
    NCBI Gene ID: 285180
    neXtProt AC: NX_Q6ZNE9
    UniProt: Q6ZNE9

  • Chr Location
    2q35; chr2:218034934-218090584 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000061815 Ensembl Gene Model | MGI Sequence Detail 22683 C57BL/6J ±  kb
transcript ENSMUST00000127134 Ensembl | MGI Sequence Detail 1841 Not Applicable  
polypeptide ENSMUSP00000115873 Ensembl | MGI Sequence Detail 563 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 5
    Primer pair 2

    Microarray probesets 1
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:227653 Terawaki S, et al., RUN and FYVE domain-containing protein 4 enhances autophagy and lysosome tethering in response to Interleukin-4. J Cell Biol. 2015 Sep 28;210(7):1133-52

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory