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Cntnap3 Gene Detail
Summary
  • Symbol
    Cntnap3
  • Name
    contactin associated protein-like 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:3588199
    NCBI Gene: 238680
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:64737591-64904029 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 33.46 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1698 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3588199
protein coding gene Chr13:64736182-64904029 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020681
protein coding gene Chr13:64764511-64928145 (-)
A/J MGP_AJ_G0020635
protein coding gene Chr13:62411087-62568137 (-)
AKR/J MGP_AKRJ_G0020612
protein coding gene Chr13:64476527-64641169 (-)
BALB/cJ MGP_BALBcJ_G0020633
protein coding gene Chr13:62841039-62996329 (-)
C3H/HeJ MGP_C3HHeJ_G0020428
protein coding gene Chr13:64016313-64173325 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021069
protein coding gene Chr13:66863886-67039643 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018645
protein coding gene Chr13:60056966-60211578 (-)
CAST/EiJ MGP_CASTEiJ_G0019945
protein coding gene Chr13:64018697-64189092 (-)
CBA/J MGP_CBAJ_G0020388
protein coding gene Chr13:69434987-69611628 (-)
DBA/2J MGP_DBA2J_G0020513
protein coding gene Chr13:62251783-62405040 (-)
FVB/NJ MGP_FVBNJ_G0020492
protein coding gene Chr13:61344256-61495139 (-)
LP/J MGP_LPJ_G0020587
protein coding gene Chr13:65059314-65221803 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020521
protein coding gene Chr13:68361389-68543700 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021111
protein coding gene Chr13:63807669-63964217 (-)
PWK/PhJ MGP_PWKPhJ_G0019699
protein coding gene Chr13:61800515-61958409 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019525
protein coding gene Chr13:61973727-62150648 (-)
WSB/EiJ MGP_WSBEiJ_G0020005
protein coding gene Chr13:64279367-64448243 (-)



Homology
more
  • Human Ortholog
    CNTNAP3, contactin associated protein family member 3
  • Vertebrate Orthologs
    3
  • Human Ortholog
    CNTNAP3, contactin associated protein family member 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CASPR3, CNTNAP3A
  • Links
    NCBI Gene ID: 79937
    neXtProt AC: NX_Q9BZ76
    UniProt: Q9BZ76

  • Chr Location
    9p12; chr9:39072767-39288303 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit normal brain morphology but impaired motor learning.
Gene Ontology
(GO)
Classifications
less
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 238680 NCBI Gene Model | MGI Sequence Detail 166439 C57BL/6J ±  kb
transcript NM_001081129 RefSeq | MGI Sequence Detail 4868 Not Specified  
polypeptide NP_001074598 RefSeq | MGI Sequence Detail 1287 Not Specified  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • InterPro Domains
    IPR000421 Coagulation factor 5/8 C-terminal domain
    IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
    IPR028873 Contactin-associated protein-like 3
    IPR000742 EGF-like domain
    IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
    IPR036056 Fibrinogen-like, C-terminal
    IPR008979 Galactose-binding-like domain superfamily
    IPR001791 Laminin G domain
Molecular
Reagents
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  • All nucleic 5
    cDNA 5

    Microarray probesets 6
References
more
  • Summaries
    All 22
    Developmental Gene Expression 4
    Phenotypes 7
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:282571 Zhang Z, et al., Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 2019 Dec;322:113055

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory