3425401B19Rik MGI Mouse Gene Detail - MGI:3588196

Symbol

3425401B19Rik
Name

RIKEN cDNA 3425401B19 gene

Feature Type

protein coding gene
IDs

MGI:3588196
NCBI Gene: 100504518
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr14:32381076-32407250 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 14, 19.40 cM
Mapping Data

1 experiment

SNPs within 2kb

247 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3588196	protein coding gene	Chr14:32381075-32430049 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0021149	protein coding gene	Chr14:25917701-25951284 (-)
A/J	MGP_AJ_G0021097	protein coding gene	Chr14:24928607-24955386 (-)
AKR/J	MGP_AKRJ_G0021074	protein coding gene	Chr14:26084437-26110899 (-)
BALB/cJ	MGP_BALBcJ_G0021101	protein coding gene	Chr14:25110325-25136229 (-)
C3H/HeJ	MGP_C3HHeJ_G0020884	protein coding gene	Chr14:25960232-25986972 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0021533	protein coding gene	Chr14:26942714-26971506 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0019095	protein coding gene	Chr14:24994940-25022525 (-)
CAST/EiJ	MGP_CASTEiJ_G0020409	protein coding gene	Chr14:25769932-25797904 (-)
CBA/J	MGP_CBAJ_G0020851	protein coding gene	Chr14:27950333-27981399 (-)
DBA/2J	MGP_DBA2J_G0020973	protein coding gene	Chr14:24954208-24980220 (-)
FVB/NJ	MGP_FVBNJ_G0020957	protein coding gene	Chr14:24921005-24947144 (-)
LP/J	MGP_LPJ_G0021042	protein coding gene	Chr14:26236096-26264761 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020983	protein coding gene	Chr14:27152932-27179718 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0021566	protein coding gene	Chr14:25876972-25902751 (-)
PWK/PhJ	MGP_PWKPhJ_G0020157	protein coding gene	Chr14:24444608-24469988 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0019981	protein coding gene	Chr14:25497016-25523812 (-)
WSB/EiJ	MGP_WSBEiJ_G0020464	protein coding gene	Chr14:25936781-25964793 (-)

Human Ortholog

C10orf71, chromosome 10 open reading frame 71

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

C10orf71, chromosome 10 open reading frame 71
Synonyms

CEFIP
Links

HGNC:26973

NCBI Gene ID: 118461

neXtProt AC: NX_Q711Q0

UniProt: Q711Q0
Chr Location

10q11.23; chr10:49297050-49327492 (+) GRCh38

MGI Vertebrate Homology

3425401B19Rik stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: C10orf71
Gene Tree

3425401B19Rik

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Phenotype Summary

4 phenotypes from 1 allele in 1 genetic background
2 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

1
Endonuclease-mediated

1
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

63 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

6
GO References

3

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

8

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

GEO

Expression Atlas

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All Sequences

45
RefSeq

18
UniProt

1
CCDS

CCDS49437.1

Ensembl

ENSMUSG00000071540 (Evidence)
NCBI Gene

100504518

			Length	Strain/Species	Flank
genomic	ENSMUSG00000071540	Ensembl Gene Model \| MGI Sequence Detail	26175	C57BL/6J	± kb
transcript	ENSMUST00000096038	Ensembl \| MGI Sequence Detail	5547	Not Applicable
polypeptide	ENSMUSP00000093741	Ensembl \| MGI Sequence Detail	1412	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000059889 cardiac-enriched FHL2-interacting protein

(term hierarchy)
InterPro Domains

IPR027838 Domain of unknown function DUF4585

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All nucleic 8

cDNA 8

Microarray probesets 3

Summaries

All 21

Gene Ontology 3

Phenotypes 2
Earliest

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
Latest

J:245587 Dierck F, et al., The novel cardiac z-disc protein CEFIP regulates cardiomyocyte hypertrophy by modulating calcineurin signaling. J Biol Chem. 2017 Sep 15;292(37):15180-15191

TSS for 3425401B19Rik:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr128019	Chr14:32407412-32407427 (-)	-170 bp
Tssr128018	Chr14:32407203-32407269 (-)	14 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23