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Acsbg2 Gene Detail
Summary
  • Symbol
    Acsbg2
  • Name
    acyl-CoA synthetase bubblegum family member 2
  • Synonyms
    Bgr
  • Feature Type
    protein coding gene
  • IDs
    MGI:3587728
    NCBI Gene: 328845
  • Gene Overview
    MyGene.info: ACSBG2
Location & Maps
more
  • Sequence Map
    Chr17:56843103-56874447 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      31345 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    ACSBG2, acyl-CoA synthetase bubblegum family member 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ACSBG2, acyl-CoA synthetase bubblegum family member 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    BGR, BRGL, PRTDNY3, PRTD-NY3
  • Links
    NCBI Gene ID: 81616
    neXtProt AC: NX_Q5FVE4

  • Chr Location
    19p13.3; chr19:6135633-6193103 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 2 alleles in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
Phenotypic analysis of mice homozygous for a gene trap allele indicates this mutation has no notable phenotype in any parameter tested.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031270 VEGA Gene Model | MGI Sequence Detail 31345 C57BL/6J ±  kb
transcript OTTMUST00000077469 VEGA | MGI Sequence Detail 2609 Not Applicable  
polypeptide OTTMUSP00000040973 VEGA | MGI Sequence Detail 667 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    100 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000003656 long-chain-fatty-acid--CoA ligase ACSBG2
  • EC
  • InterPro Domains
    IPR020845 AMP-binding, conserved site
    IPR000873 AMP-dependent synthetase/ligase
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory