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Lrp3 Gene Detail
Summary
  • Symbol
    Lrp3
  • Name
    low density lipoprotein receptor-related protein 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:3584516
    NCBI Gene: 435965
  • Gene Overview
    MyGene.info: LRP3
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:35200878-35215493 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 21.15 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    89 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3584516
protein coding gene Chr7:35200027-35215498 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032084
protein coding gene Chr7:34558133-34574902 (-)
A/J MGP_AJ_G0032064
protein coding gene Chr7:33652346-33667833 (-)
AKR/J MGP_AKRJ_G0031997
protein coding gene Chr7:34452214-34467689 (-)
BALB/cJ MGP_BALBcJ_G0032071
protein coding gene Chr7:33944004-33959874 (-)
C3H/HeJ MGP_C3HHeJ_G0031788
protein coding gene Chr7:35352093-35367560 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032548
protein coding gene Chr7:36269001-36284532 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029581
protein coding gene Chr7:34371629-34386782 (-)
CAST/EiJ MGP_CASTEiJ_G0031123
protein coding gene Chr7:26494541-26578422 (-)
CBA/J MGP_CBAJ_G0031756
protein coding gene Chr7:37405801-37421272 (-)
DBA/2J MGP_DBA2J_G0031908
protein coding gene Chr7:33493239-33508707 (-)
FVB/NJ MGP_FVBNJ_G0031863
protein coding gene Chr7:33425345-33441686 (-)
LP/J MGP_LPJ_G0031985
protein coding gene Chr7:34893915-34910551 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031901
protein coding gene Chr7:36420477-36437633 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032563
protein coding gene Chr7:33998419-34014084 (-)
PWK/PhJ MGP_PWKPhJ_G0030845
protein coding gene Chr7:26825072-26905229 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030680
protein coding gene Chr7:23575469-23590404 (-)
WSB/EiJ MGP_WSBEiJ_G0031233
protein coding gene Chr7:34545263-34560728 (-)



Homology
more
  • Human Ortholog
    LRP3, LDL receptor related protein 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    LRP3, LDL receptor related protein 3
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 4037
    neXtProt AC: NX_O75074
    UniProt: O75074

  • Chr Location
    19q13.11; chr19:33194693-33208867 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 1745
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: LRP3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 435965 NCBI Gene Model | MGI Sequence Detail 14616 C57BL/6J ±  kb
transcript NM_001024707 RefSeq | MGI Sequence Detail 4007 C57BL/6  
polypeptide NP_001019878 RefSeq | MGI Sequence Detail 790 C57BL/6  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • InterPro Domains
    IPR000859 CUB domain
    IPR036055 LDL receptor-like superfamily
    IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved site
    IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
    IPR035914 Spermadhesin, CUB domain superfamily
Molecular
Reagents
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  • All nucleic 6
    cDNA 6

    Microarray probesets 1
References
more
  • Summaries
    All 19
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory