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Fbxw20 Gene Detail
Summary
  • Symbol
    Fbxw20
  • Name
    F-box and WD-40 domain protein 20
  • Feature Type
    protein coding gene
  • IDs
    MGI:3584372
    NCBI Gene: 434440
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr9:109046500-109063822 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 59.63 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    28 from dbSNP Build 142
  • Strain Annotations
    10
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3584372
protein coding gene Chr9:109046500-109063822 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0035312
protein coding gene Chr9:107299134-107739647 (-)
AKR/J MGP_AKRJ_G0035241
protein coding gene Chr9:109810754-110156680 (-)
BALB/cJ MGP_BALBcJ_G0035306
protein coding gene Chr9:106857622-107425301 (-)
C3H/HeJ MGP_C3HHeJ_G0035013
protein coding gene Chr9:110212385-110611322 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035823
protein coding gene Chr9:114226230-114245824 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0034981
protein coding gene Chr9:118301813-118728829 (-)
DBA/2J no annotation
FVB/NJ no annotation
LP/J MGP_LPJ_G0035220
protein coding gene Chr9:111464296-112156842 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0035845
protein coding gene Chr9:110112831-110759291 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0033867
protein coding gene Chr9:110529382-110657108 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    FBXW12, F-box and WD repeat domain containing 12
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBXW12, F-box and WD repeat domain containing 12
  • Synonyms
    FBW12, FBXO12, FBXO35
  • Links
    NCBI Gene ID: 285231
    neXtProt AC: NX_Q6X9E4
    UniProt: Q6X9E4

  • Chr Location
    3p21.31; chr3:48372219-48394830 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotypes from 1 allele in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 434440 NCBI Gene Model | MGI Sequence Detail 17323 C57BL/6J ±  kb
    transcript NM_001008428 RefSeq | MGI Sequence Detail 1511 C57BL/6  
    polypeptide NP_001008428 RefSeq | MGI Sequence Detail 468 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • InterPro Domains
      IPR001810 F-box domain
      IPR036047 F-box-like domain superfamily
      IPR036322 WD40-repeat-containing domain superfamily
      IPR015943 WD40/YVTN repeat-like-containing domain superfamily
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 1
    References
    more
    • Summaries
      All 16
      Phenotypes 2
    • Earliest
      J:93441 Jin J, et al., Systematic analysis and nomenclature of mammalian F-box proteins. Genes Dev. 2004 Dec 1;18(21):2573-80
    • Latest
      J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    10/12/2021
    MGI 6.17
    The Jackson Laboratory