Xkrx Gene Detail

Summary

• Symbol
  Xkrx
• Name
  X-linked Kx blood group related, X-linked

• Feature Type
  protein coding gene
• IDs
  MGI:3584011
  NCBI Gene: 331524

Location & Maps

• Sequence Map
  ChrX:134149043-134162076 bp, - strand
• From VEGA annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    13034 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome X, 55.85 cM
• Mapping Data
  1 experiment

Homology

• Human Ortholog
  XKRX, XK related, X-linked

• Vertebrate Orthologs
  10

• Human Ortholog
  XKRX, XK related, X-linked
  Orthology source: HomoloGene, HGNC
• Synonyms
  XKR2, XPLAC, XRG2
• Links
  HGNC:29845

  NCBI Gene ID: 402415

  neXtProt AC: NX_Q6PP77

  UniProt: Q6PP77

  
  
• Chr Location
  Xq22.1; chrX:100886924-100957401 (-)  GRCh38.p7

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• HomoloGene
  Vertebrate Homology Class 77932
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  
• HCOP
  human homology predictions: XKRX
• Gene Tree
  Xkrx
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotypes from 1 allele in 1 genetic background
  6 phenotype references
  

• All Mutations and Alleles
  3
• Targeted
  3
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  7 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  3
• GO References
  2

• External Resources
  FuncBase

Expression

• cDNA Data
  6

• Other Mouse Links
  GEO
  Expression Atlas
• Other Vertebrate Links
  ZFIN xkrx

Interactions

• Xkrx interacts with 195 markers (Mir7-1, Mir9-1, Mir9-2, ...) View All

Sequences &
Gene Models

• All Sequences
  30
• RefSeq
  12
• UniProt
  2
• CCDS
  CCDS30391.1
• UniGene
  235055

• VEGA
  OTTMUSG00000019158 (Evidence)
• Ensembl
  ENSMUSG00000031258 (Evidence)
• NCBI Gene
  331524

Representative Sequences			Length	Strain/Species
genomic	OTTMUSG00000019158	VEGA Gene Model | MGI Sequence Detail	13034	C57BL/6J
transcript	OTTMUST00000045923	VEGA | MGI Sequence Detail	2876	Not Applicable
polypeptide	OTTMUSP00000020696	VEGA | MGI Sequence Detail	449	Not Applicable

Polymorphisms

• SNPs within 2kb
  81 from dbSNP Build 142

Protein
Information

• UniProt
  2 Sequences
• Protein Ontology
  PR:000017489 XK-related protein 2
  (term hierarchy)
• InterPro Domains
  IPR018629 XK-related protein

Molecular
Reagents

• All nucleic 7

  Genomic 1

  cDNA 6

  
  

  Microarray probesets 2

References

• Summaries
  All 25

  Gene Ontology 2

  Phenotypes 6
• Earliest
  J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
• Latest
  J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514