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Mindy4 Gene Detail
Summary
  • Symbol
    Mindy4
  • Name
    MINDY lysine 48 deubiquitinase 4
  • Synonyms
    C330043M08Rik, Fam188b, LOC384387
  • Feature Type
    protein coding gene
  • IDs
    MGI:3583959
    NCBI Gene: 330323
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:55180368-55297207 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 27.38 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    887 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3583959
 protein coding gene Chr6:55180337-55297208 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030771
 protein coding gene Chr6:54604955-54721742 (+)
A/J MGP_AJ_G0030740
 protein coding gene Chr6:52067684-52181152 (+)
AKR/J MGP_AKRJ_G0030667
 protein coding gene Chr6:53840854-53956954 (+)
BALB/cJ MGP_BALBcJ_G0030752
 protein coding gene Chr6:52444067-52553884 (+)
C3H/HeJ MGP_C3HHeJ_G0030465
 protein coding gene Chr6:53862789-53980634 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031207
 protein coding gene Chr6:55822320-55948929 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028413
 protein coding gene Chr6:49675238-49790577 (+)
CAST/EiJ MGP_CASTEiJ_G0029868
 protein coding gene Chr6:53713232-53832119 (+)
CBA/J MGP_CBAJ_G0030439
 protein coding gene Chr6:58122094-58244358 (+)
DBA/2J MGP_DBA2J_G0030589
 protein coding gene Chr6:51967150-52079982 (+)
FVB/NJ MGP_FVBNJ_G0030541
 protein coding gene Chr6:51562130-51679433 (+)
LP/J MGP_LPJ_G0030674
 protein coding gene Chr6:54539038-54656084 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030575
 protein coding gene Chr6:60627504-60746850 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031237
 protein coding gene Chr6:53805057-53927024 (+)
PWK/PhJ MGP_PWKPhJ_G0029581
 protein coding gene Chr6:51633539-51745228 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029415
 protein coding gene Chr6:53191602-53308965 (+)
WSB/EiJ MGP_WSBEiJ_G0029945
 protein coding gene Chr6:53833889-53955923 (+)



Homology
more
  • Human Ortholog
    MINDY4, MINDY lysine 48 deubiquitinase 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MINDY4, MINDY lysine 48 deubiquitinase 4
  • Synonyms
    AQP1, AQP-1, C7orf67, CHIP28, FAM188B
  • Links
    NCBI Gene ID: 84182
    neXtProt AC: NX_Q4G0A6
    UniProt: Q4G0A6

  • Chr Location
    7p14.3; chr7:30771417-30892387 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    3
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    16
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038022 Ensembl Gene Model | MGI Sequence Detail 116840 C57BL/6J ±  kb
transcript ENSMUST00000053094 Ensembl | MGI Sequence Detail 4270 Not Applicable  
polypeptide ENSMUSP00000061221 Ensembl | MGI Sequence Detail 744 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 2
Other
Accession IDs
less
MGI:2686252
References
more
  • Summaries
    All 25
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory