Svs3b Gene Detail

Summary

• Symbol
  Svs3b
• Name
  seminal vesicle secretory protein 3B
• Synonyms
  9530004A22Rik, SVS III

• Feature Type
  protein coding gene
• IDs
  MGI:3583778
  NCBI Gene: 329557
• Alliance
  genome feature page
• Transcription Start Sites
  9 TSS

Location &
Maps

• Sequence Map
  Chr2:164096283-164098560 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 2, 84.91 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  253 from dbSNP Build 142
• Strain Annotations
  17

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3583778	protein coding gene	Chr2:164096283-164098563 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0026843	protein coding gene	Chr2:169642760-169645039 (-)
A/J	MGP_AJ_G0026810	protein coding gene	Chr2:162813905-162816533 (+)
AKR/J	MGP_AKRJ_G0026780	protein coding gene	Chr2:167599323-167604662 (-)
BALB/cJ	MGP_BALBcJ_G0026819	protein coding gene	Chr2:163153617-163157598 (+)
C3H/HeJ	MGP_C3HHeJ_G0026560	protein coding gene	Chr2:167954467-167961053 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0027266	protein coding gene	Chr2:174582811-174585088 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0024637	protein coding gene	Chr2:156192124-156194370 (-)
CAST/EiJ	MGP_CASTEiJ_G0026021	protein coding gene	Chr2:168381999-168386934 (-)
CBA/J	MGP_CBAJ_G0026537	protein coding gene	Chr2:180879704-180881981 (-)
DBA/2J	MGP_DBA2J_G0026675	protein coding gene	Chr2:161947969-161951210 (-)
FVB/NJ	MGP_FVBNJ_G0026641	protein coding gene	Chr2:160322731-160325009 (-)
LP/J	MGP_LPJ_G0026778	protein coding gene	Chr2:169749288-169751569 (-)
NOD/ShiLtJ	no annotation
NZO/HlLtJ	MGP_NZOHlLtJ_G0027323	protein coding gene	Chr2:167545884-167547954 (+)
PWK/PhJ	MGP_PWKPhJ_G0025755	protein coding gene	Chr2:161527004-161531759 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0025567	protein coding gene	Chr2:166603397-166604460 (+)
WSB/EiJ	MGP_WSBEiJ_G0026091	protein coding gene	Chr2:168367069-168370974 (-)

Homology

• MGI Vertebrate Homology
  Svs3b stringent orthology
  1 mouse;1 rat
  
• Gene Tree
  Svs3b
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotype references
  

• All Mutations and Alleles
  2
• Endonuclease-mediated
  1
• Genomic Mutations
  1 involving Svs3b
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  10 strains or lines available

Expression

• Assay Results
  706
• cDNA Data
  1

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  27
• RefSeq
  2
• UniProt
  2
• CCDS
  CCDS38321.1

• Ensembl
  ENSMUSG00000050383 (Evidence)
• NCBI Gene
  329557

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000050383	Ensembl Gene Model | MGI Sequence Detail	2278	C57BL/6J
transcript	ENSMUST00000063132	Ensembl | MGI Sequence Detail	1249	Not Applicable
polypeptide	ENSMUSP00000062011	Ensembl | MGI Sequence Detail	265	Not Applicable

Protein
Information

• UniProt
  2 Sequences

Molecular
Reagents

• All nucleic 1

  cDNA 1

  
  

  Microarray probesets 1

References

• Summaries
  All 14

  Phenotypes 3
• Earliest
  J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
• Latest
  J:291572 Shindo M, et al., Deletion of a Seminal Gene Cluster Reinforces a Crucial Role of SVS2 in Male Fertility. Int J Mol Sci. 2019 Sep 14;20(18):4557

TSS for Svs3b:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr27408	Chr2:164098625-164098631 (-)	-68 bp
Tssr27407	Chr2:164098558-164098563 (-)	-1 bp
Tssr27406	Chr2:164098192-164098229 (-)	349 bp
Tssr27405	Chr2:164096667-164096675 (-)	1,889 bp
Tssr27404	Chr2:164096630-164096641 (-)	1,924 bp
Tssr27403	Chr2:164096613-164096629 (-)	1,939 bp
Tssr27402	Chr2:164096591-164096603 (-)	1,963 bp
Tssr27401	Chr2:164096529-164096538 (-)	2,026 bp
Tssr27400	Chr2:164096422-164096433 (-)	2,132 bp