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Nms Gene Detail
Summary
  • Symbol
    Nms
  • Name
    neuromedin S
  • Feature Type
    protein coding gene
  • IDs
    MGI:3583618
    NCBI Gene: 433292
Location & Maps
more
  • Sequence Map
    Chr1:38939149-38950276 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      11128 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 17.31 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    NMS, neuromedin S
  • Vertebrate Orthologs
    7
  • Human Ortholog
    NMS, neuromedin S
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 129521
    neXtProt AC: NX_Q5H8A3

  • Chr Location
    2q11.2; chr2:100470482-100483280 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Targeted
    7
  • Genomic Mutations
    1 involving Nms
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035128 VEGA Gene Model | MGI Sequence Detail 11128 C57BL/6J ±  kb
transcript OTTMUST00000089402 VEGA | MGI Sequence Detail 1001 Not Applicable  
polypeptide OTTMUSP00000048861 VEGA | MGI Sequence Detail 153 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    164 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000011293 neuromedin-S
  • InterPro Domains
    IPR018070 Neuromedin U, amidation site
Molecular
Reagents
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  • All nucleic 1
    cDNA 1

    Microarray probesets 1
References
more
  • Summaries
    All 20
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:98692 Mori K, et al., Identification of neuromedin S and its possible role in the mammalian circadian oscillator system. EMBO J. 2005 Jan 26;24(2):325-35
  • Latest
    J:219926 Lee IT, et al., Neuromedin s-producing neurons act as essential pacemakers in the suprachiasmatic nucleus to couple clock neurons and dictate circadian rhythms. Neuron. 2015 Mar 4;85(5):1086-102

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory