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Ugt1a6b Gene Detail
Summary
  • Symbol
    Ugt1a6b
  • Name
    UDP glucuronosyltransferase 1 family, polypeptide A6B
  • Synonyms
    A9'
  • Feature Type
    protein coding gene
  • IDs
    MGI:3580629
    NCBI Gene: 394435
  • Member of
    Ugt1 cluster
  • Gene Overview
    MyGene.info: UGT1A6
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:88103257-88218998 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 44.51 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1110 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3580629
protein coding gene Chr1:88103252-88219003 (.)
129S1/SvImJ MGP_129S1SvImJ_G0016282
protein coding gene Chr1:89615532-89628377 (+)
A/J MGP_AJ_G0016258
protein coding gene Chr1:86163433-86334105 (+)
AKR/J MGP_AKRJ_G0016219
protein coding gene Chr1:88761301-88898487 (+)
BALB/cJ MGP_BALBcJ_G0016215
protein coding gene Chr1:86329671-86472418 (+)
C3H/HeJ MGP_C3HHeJ_G0016043
protein coding gene Chr1:88975081-89122343 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016673
protein coding gene Chr1:92842928-92996660 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014391
protein coding gene Chr1:80583529-80707873 (+)
CAST/EiJ MGP_CASTEiJ_G0015629
protein coding gene Chr1:88190952-88339178 (+)
CBA/J MGP_CBAJ_G0016019
protein coding gene Chr1:95831932-95995699 (+)
DBA/2J MGP_DBA2J_G0016122
protein coding gene Chr1:85444817-85575533 (+)
FVB/NJ MGP_FVBNJ_G0016121
protein coding gene Chr1:84521429-84658653 (+)
LP/J MGP_LPJ_G0016197
protein coding gene Chr1:90688836-90703609 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0016715
protein coding gene Chr1:88808838-88953954 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0015196
protein coding gene Chr1:87776597-87876023 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    UGT1A6, UDP glucuronosyltransferase family 1 member A6
  • Vertebrate Orthologs
    7
  • Human Ortholog
    UGT1A6, UDP glucuronosyltransferase family 1 member A6
    Orthology source: HomoloGene
  • Synonyms
    GNT1, HLUGP, HLUGP1, hUG-BR1, UDPGT, UDPGT 1-6, UGT1, UGT1-01, UGT1-03, UGT1-05, UGT1.1, UGT1.3, UGT1.5, UGT1A, UGT-1A, UGT1A1, UGT1A3, UGT1A5, UGT1A6S, UGT1C, UGT-1C, UGT1E, UGT-1E, UGT1F
  • Links
    NCBI Gene ID: 54578
    neXtProt AC: NX_P19224
    UniProt: P19224

  • Chr Location
    2q37.1; chr2:233691675-233773305 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 394435 NCBI Gene Model | MGI Sequence Detail 115742 C57BL/6J ±  kb
transcript NM_201410 RefSeq | MGI Sequence Detail 2293 C57BL/6  
polypeptide NP_958812 RefSeq | MGI Sequence Detail 531 C57BL/6  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • EC
  • InterPro Domains
    IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase
    IPR035595 UDP-glycosyltransferase family, conserved site
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2
References
more
  • Summaries
    All 20
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory