Dgkk
Gene Detail

Symbol Name ID

Dgkk diacylglycerol kinase kappa MGI:3580254

Feature Type

protein coding gene

Genetic Map

Chromosome X

3.07 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

ChrX:6873484-6948363 bp, + strand From VEGA annotation of GRCm38   74880 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:45867  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Dgkk

Human homologs

Human Homolog		DGKK, diacylglycerol kinase, kappa
NCBI Gene ID		139189
neXtProt AC		NX_Q5KSL6
Human Chr (Location)		Xp11.22; chrX:50111879-50213721 (-)  GRCh37.p10

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Process	diacylglycerol metabolic process, intracellular signal transduction, ...
Component	plasma membrane
Function	diacylglycerol kinase activity, kinase activity

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (28)    Tissues (5)    Images (21)
Theiler Stages: 23, 28

Assay Type	Results
RNA in situ	26
RT-PCR	2

cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(5) cDNA(4) Primer pair(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000016656 (Evidence)
Ensembl Gene Model	ENSMUSG00000062393 (Evidence)
Entrez Gene	331374 (Evidence)
DFCI	TC1588003, TC1589514
DoTS	DT.40164806
NIA Mouse Gene Index	U019652
International Mouse Knockout Project Status	Dgkk

Sequences

Length	Strain/Species
genomic	OTTMUSG00000016656	VEGA Gene Model | MGI Sequence Detail	74880	C57BL/6J
transcript	OTTMUST00000040322	VEGA | MGI Sequence Detail	6827	Not Applicable
polypeptide	OTTMUSP00000018015	VEGA | MGI Sequence Detail	1062	Not Applicable

All sequences(23) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(292 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000756	Diacylglycerol kinase, accessory domain
InterPro	IPR001206	Diacylglycerol kinase, catalytic domain
InterPro	IPR001849	Pleckstrin homology domain
InterPro	IPR011993	Pleckstrin homology-like domain
InterPro	IPR002219	Protein kinase C-like, phorbol ester/diacylglycerol binding

References

(Earliest) J:115297 Crotty T, et al., Diacylglycerol kinase delta regulates protein kinase C and epidermal growth factor receptor signaling. Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15485-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(22)