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Dgkk
Gene Detail
Symbol

Name
ID
Dgkk
diacylglycerol kinase kappa
MGI:3580254
Feature Type
protein coding gene
Genetic Map
Chromosome X
3.07 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
ChrX:6873484-6948363 bp, + strand
From VEGA annotation of GRCm38

  74880 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:45867  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Dgkk

Human
homologs
Human Homolog DGKK, diacylglycerol kinase, kappa
NCBI Gene ID 139189
neXtProt AC  NX_Q5KSL6
Human Chr (Location)  Xp11.22; chrX:50368880-50470722 (-)  GRCh38
Interactions
Dgkk interacts with 465 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process diacylglycerol metabolic process, intracellular signal transduction, ...
Component intracellular, plasma membrane
Function ATP binding, diacylglycerol kinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (28)    Tissues (5)    Images (21)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 26
RT-PCR 2
cDNA source data(4)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(5) cDNA(4) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000016656 (Evidence)
Ensembl Gene ModelENSMUSG00000062393 (Evidence)
Entrez Gene331374 (Evidence)
DFCITC1588003, TC1589514
DoTSDT.40164806
NIA Mouse Gene IndexU019652
EC2.7.1.107
International Mouse Knockout Project StatusDgkk
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016656 VEGA Gene Model | MGI Sequence Detail 74880 C57BL/6J ±  kb
transcript OTTMUST00000040322 VEGA | MGI Sequence Detail 6827 Not Applicable 
polypeptide OTTMUSP00000018015 VEGA | MGI Sequence Detail 1062 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(2) UniProt(4)
Polymorphisms
SNPs within 2kb(372 from dbSNP Build 137)    SNPs within 2kb including multiple locations(374)
Protein-related
information
ResourceIDDescription
InterPro IPR016064 ATP-NAD kinase-like domain
InterPro IPR000756 Diacylglycerol kinase, accessory domain
InterPro IPR001206 Diacylglycerol kinase, catalytic domain
InterPro IPR001849 Pleckstrin homology domain
InterPro IPR011993 Pleckstrin homology-like domain
InterPro IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol binding
References
(Earliest) J:115297 Crotty T, et al., Diacylglycerol kinase delta regulates protein kinase C and epidermal growth factor receptor signaling. Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15485-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(22)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory